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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SAE1
All Species:
30.3
Human Site:
T261
Identified Species:
47.62
UniProt:
Q9UBE0
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBE0
NP_005491.1
346
38450
T261
G
R
D
P
S
S
D
T
Y
E
E
D
S
E
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001109956
343
37452
T262
G
R
D
P
S
S
D
T
Y
E
E
D
S
E
L
Dog
Lupus familis
XP_533632
346
38307
T261
G
R
D
P
S
S
D
T
F
G
E
D
S
E
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9R1T2
350
38602
S265
G
R
D
P
T
S
E
S
Y
K
E
D
A
E
L
Rat
Rattus norvegicus
Q6AXQ0
349
38494
S264
G
R
D
P
T
S
D
S
Y
S
E
D
A
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521826
313
34323
P251
L
E
S
L
G
V
S
P
D
V
L
P
D
D
F
Chicken
Gallus gallus
Q5ZIE6
535
60465
R327
G
Q
G
C
L
P
V
R
G
T
I
P
D
M
I
Frog
Xenopus laevis
Q8JGT5
344
38228
S259
G
R
D
P
Q
P
S
S
Y
Q
E
D
S
E
L
Zebra Danio
Brachydanio rerio
Q6IQS6
348
39058
S263
G
R
D
P
Q
P
D
S
F
A
E
D
S
Q
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VTE9
524
58698
I439
G
N
I
P
G
E
C
I
V
E
Q
D
I
G
R
Honey Bee
Apis mellifera
XP_394348
287
32309
K228
K
K
F
D
L
E
N
K
I
N
H
L
V
E
G
Nematode Worm
Caenorhab. elegans
Q17820
343
38720
E257
N
K
L
T
G
V
T
E
N
D
I
E
K
L
I
Sea Urchin
Strong. purpuratus
XP_794964
338
37736
S253
G
R
K
P
E
A
A
S
S
E
N
D
S
T
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P42744
540
60016
S339
G
S
I
P
D
M
T
S
S
T
E
H
Y
I
N
Baker's Yeast
Sacchar. cerevisiae
Q06624
347
39255
S265
N
Q
K
G
K
A
I
S
F
E
Q
M
K
R
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
82.3
96.2
N.A.
92.2
91.4
N.A.
77.1
20.9
74.8
68.6
N.A.
21.3
41.6
32
48.5
Protein Similarity:
100
N.A.
86.7
98.8
N.A.
97.4
96.2
N.A.
84.6
36.2
86.4
82.7
N.A.
36
60.9
50.5
65.9
P-Site Identity:
100
N.A.
100
86.6
N.A.
66.6
73.3
N.A.
0
6.6
66.6
60
N.A.
26.6
6.6
0
40
P-Site Similarity:
100
N.A.
100
93.3
N.A.
100
93.3
N.A.
6.6
20
80
80
N.A.
33.3
20
26.6
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.4
33.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.5
55.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
14
7
0
0
7
0
0
14
0
0
% A
% Cys:
0
0
0
7
0
0
7
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
47
7
7
0
34
0
7
7
0
60
14
7
7
% D
% Glu:
0
7
0
0
7
14
7
7
0
34
54
7
0
47
7
% E
% Phe:
0
0
7
0
0
0
0
0
20
0
0
0
0
0
7
% F
% Gly:
74
0
7
7
20
0
0
0
7
7
0
0
0
7
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
7
7
0
0
0
% H
% Ile:
0
0
14
0
0
0
7
7
7
0
14
0
7
7
14
% I
% Lys:
7
14
14
0
7
0
0
7
0
7
0
0
14
0
0
% K
% Leu:
7
0
7
7
14
0
0
0
0
0
7
7
0
7
47
% L
% Met:
0
0
0
0
0
7
0
0
0
0
0
7
0
7
0
% M
% Asn:
14
7
0
0
0
0
7
0
7
7
7
0
0
0
7
% N
% Pro:
0
0
0
67
0
20
0
7
0
0
0
14
0
0
0
% P
% Gln:
0
14
0
0
14
0
0
0
0
7
14
0
0
7
0
% Q
% Arg:
0
54
0
0
0
0
0
7
0
0
0
0
0
7
7
% R
% Ser:
0
7
7
0
20
34
14
47
14
7
0
0
40
0
0
% S
% Thr:
0
0
0
7
14
0
14
20
0
14
0
0
0
7
0
% T
% Val:
0
0
0
0
0
14
7
0
7
7
0
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
34
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _