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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SAE1
All Species:
25.45
Human Site:
S225
Identified Species:
40
UniProt:
Q9UBE0
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBE0
NP_005491.1
346
38450
S225
E
A
L
E
V
D
W
S
S
E
K
A
K
A
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001109956
343
37452
S226
E
A
L
E
V
D
W
S
S
E
K
A
K
A
A
Dog
Lupus familis
XP_533632
346
38307
S225
E
A
L
E
V
D
W
S
S
D
K
A
K
A
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9R1T2
350
38602
S229
E
A
L
E
V
D
W
S
G
E
K
A
K
A
A
Rat
Rattus norvegicus
Q6AXQ0
349
38494
S228
E
A
L
A
V
D
W
S
G
E
K
A
Q
A
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521826
313
34323
K215
F
L
L
Q
V
L
L
K
F
R
T
D
K
G
R
Chicken
Gallus gallus
Q5ZIE6
535
60465
N291
R
C
I
E
E
I
F
N
D
D
C
C
V
N
L
Frog
Xenopus laevis
Q8JGT5
344
38228
R223
D
A
L
E
I
D
W
R
S
E
K
A
K
S
A
Zebra Danio
Brachydanio rerio
Q6IQS6
348
39058
T227
E
A
L
E
V
D
W
T
T
E
K
A
K
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VTE9
524
58698
P403
E
K
S
S
R
L
L
P
L
V
E
D
N
E
L
Honey Bee
Apis mellifera
XP_394348
287
32309
L192
Q
I
S
E
S
V
M
L
N
Y
R
E
K
Y
G
Nematode Worm
Caenorhab. elegans
Q17820
343
38720
T221
E
T
L
N
S
D
F
T
A
K
K
I
V
R
K
Sea Urchin
Strong. purpuratus
XP_794964
338
37736
W217
K
E
C
F
D
K
D
W
S
S
L
T
E
K
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P42744
540
60016
N303
N
D
S
C
A
E
V
N
S
N
S
S
A
F
W
Baker's Yeast
Sacchar. cerevisiae
Q06624
347
39255
T229
N
E
V
L
S
T
A
T
L
K
E
K
M
T
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
82.3
96.2
N.A.
92.2
91.4
N.A.
77.1
20.9
74.8
68.6
N.A.
21.3
41.6
32
48.5
Protein Similarity:
100
N.A.
86.7
98.8
N.A.
97.4
96.2
N.A.
84.6
36.2
86.4
82.7
N.A.
36
60.9
50.5
65.9
P-Site Identity:
100
N.A.
100
93.3
N.A.
93.3
80
N.A.
20
6.6
73.3
73.3
N.A.
6.6
13.3
26.6
6.6
P-Site Similarity:
100
N.A.
100
100
N.A.
93.3
86.6
N.A.
26.6
33.3
93.3
100
N.A.
13.3
33.3
53.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.4
33.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.5
55.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
47
0
7
7
0
7
0
7
0
0
47
7
34
40
% A
% Cys:
0
7
7
7
0
0
0
0
0
0
7
7
0
0
0
% C
% Asp:
7
7
0
0
7
54
7
0
7
14
0
14
0
0
0
% D
% Glu:
54
14
0
54
7
7
0
0
0
40
14
7
7
7
0
% E
% Phe:
7
0
0
7
0
0
14
0
7
0
0
0
0
7
0
% F
% Gly:
0
0
0
0
0
0
0
0
14
0
0
0
0
7
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
7
7
0
7
7
0
0
0
0
0
7
0
0
0
% I
% Lys:
7
7
0
0
0
7
0
7
0
14
54
7
54
7
7
% K
% Leu:
0
7
60
7
0
14
14
7
14
0
7
0
0
0
14
% L
% Met:
0
0
0
0
0
0
7
0
0
0
0
0
7
0
0
% M
% Asn:
14
0
0
7
0
0
0
14
7
7
0
0
7
7
0
% N
% Pro:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% P
% Gln:
7
0
0
7
0
0
0
0
0
0
0
0
7
0
14
% Q
% Arg:
7
0
0
0
7
0
0
7
0
7
7
0
0
7
7
% R
% Ser:
0
0
20
7
20
0
0
34
40
7
7
7
0
14
7
% S
% Thr:
0
7
0
0
0
7
0
20
7
0
7
7
0
7
0
% T
% Val:
0
0
7
0
47
7
7
0
0
7
0
0
14
0
0
% V
% Trp:
0
0
0
0
0
0
47
7
0
0
0
0
0
0
7
% W
% Tyr:
0
0
0
0
0
0
0
0
0
7
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _