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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MYO1A
All Species:
22.73
Human Site:
S291
Identified Species:
55.56
UniProt:
Q9UBC5
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBC5
NP_005370.1
1043
118401
S291
Q
A
S
G
I
P
A
S
G
I
R
D
G
R
G
Chimpanzee
Pan troglodytes
XP_509152
1043
118369
S291
Q
A
N
G
I
P
A
S
G
I
R
D
G
R
G
Rhesus Macaque
Macaca mulatta
XP_001115546
1043
118260
S291
Q
A
N
G
T
P
A
S
G
I
R
D
G
R
G
Dog
Lupus familis
XP_531642
1041
118786
S291
Q
A
N
G
V
S
A
S
S
I
R
D
G
K
G
Cat
Felis silvestris
Mouse
Mus musculus
O88329
1043
118676
S291
Q
A
N
G
I
P
A
S
G
I
C
D
G
K
G
Rat
Rattus norvegicus
Q62774
842
97192
D156
S
R
F
G
K
Y
M
D
I
E
F
D
F
K
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P47807
1045
119259
S294
Q
A
S
G
M
E
A
S
S
I
T
E
P
R
E
Frog
Xenopus laevis
A0MP03
1028
118817
T296
H
S
H
A
Q
V
T
T
E
N
Q
I
K
Y
I
Zebra Danio
Brachydanio rerio
A5PF48
1026
118045
T297
E
G
E
T
H
I
T
T
E
A
Q
L
Q
F
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q23979
1035
118971
S304
E
G
N
A
K
V
N
S
R
D
L
V
V
T
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
96.6
89.2
N.A.
87.6
70.8
N.A.
N.A.
64
42.5
41.3
N.A.
43.7
N.A.
N.A.
N.A.
Protein Similarity:
100
99.9
98.7
94.8
N.A.
94.3
76.1
N.A.
N.A.
79.6
61.8
61.5
N.A.
62.6
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
86.6
66.6
N.A.
80
20
N.A.
N.A.
53.3
0
0
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
86.6
N.A.
93.3
26.6
N.A.
N.A.
66.6
20
20
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
60
0
20
0
0
60
0
0
10
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
10
0
10
0
60
0
0
0
% D
% Glu:
20
0
10
0
0
10
0
0
20
10
0
10
0
0
10
% E
% Phe:
0
0
10
0
0
0
0
0
0
0
10
0
10
10
0
% F
% Gly:
0
20
0
70
0
0
0
0
40
0
0
0
50
0
60
% G
% His:
10
0
10
0
10
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
30
10
0
0
10
60
0
10
0
0
10
% I
% Lys:
0
0
0
0
20
0
0
0
0
0
0
0
10
30
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
10
10
0
0
10
% L
% Met:
0
0
0
0
10
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
50
0
0
0
10
0
0
10
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
40
0
0
0
0
0
0
10
0
0
% P
% Gln:
60
0
0
0
10
0
0
0
0
0
20
0
10
0
0
% Q
% Arg:
0
10
0
0
0
0
0
0
10
0
40
0
0
40
0
% R
% Ser:
10
10
20
0
0
10
0
70
20
0
0
0
0
0
0
% S
% Thr:
0
0
0
10
10
0
20
20
0
0
10
0
0
10
0
% T
% Val:
0
0
0
0
10
20
0
0
0
0
0
10
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _