KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPS15L1
All Species:
26.67
Human Site:
T474
Identified Species:
48.89
UniProt:
Q9UBC2
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBC2
NP_067058.1
864
94255
T474
R
Q
K
C
Q
D
E
T
Q
M
I
S
S
L
K
Chimpanzee
Pan troglodytes
XP_001139238
933
102460
A460
R
K
K
C
A
E
E
A
Q
L
I
S
S
L
K
Rhesus Macaque
Macaca mulatta
XP_001113811
1015
110551
T579
R
Q
K
C
Q
D
E
T
Q
M
I
S
S
L
K
Dog
Lupus familis
XP_541965
908
99427
T472
R
Q
K
C
Q
D
E
T
Q
M
I
S
S
L
K
Cat
Felis silvestris
Mouse
Mus musculus
Q60902
907
99276
T472
R
Q
K
C
Q
D
E
T
Q
T
I
S
S
L
K
Rat
Rattus norvegicus
NP_001025092
878
96428
T474
R
Q
K
C
Q
D
E
T
Q
T
I
S
S
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418263
887
97653
T497
R
Q
K
C
Q
E
E
T
Q
V
I
S
S
L
K
Frog
Xenopus laevis
O42287
1270
143652
E574
K
R
A
L
E
T
K
E
I
G
R
Q
Q
L
R
Zebra Danio
Brachydanio rerio
XP_696575
951
104620
S535
R
Q
K
C
Q
E
E
S
Q
M
I
S
S
L
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_726481
1106
119588
E505
R
D
Q
C
H
M
Q
E
V
T
I
N
E
Q
E
Honey Bee
Apis mellifera
XP_001122937
1043
116535
Q462
E
Q
K
I
H
E
E
Q
K
K
V
D
K
L
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001192039
1179
125310
Q221
Q
S
Q
C
Q
E
V
Q
K
S
V
D
S
L
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SAT8
1533
164753
F890
V
E
D
S
V
R
E
F
A
K
G
I
E
D
S
Conservation
Percent
Protein Identity:
100
44.2
83.9
90.5
N.A.
87.6
88.5
N.A.
N.A.
82
21.1
61.6
N.A.
31.2
34.1
N.A.
32.6
Protein Similarity:
100
61.5
84.1
92.1
N.A.
91.1
91.3
N.A.
N.A.
90.1
36.2
72.9
N.A.
46.4
49.9
N.A.
46.3
P-Site Identity:
100
66.6
100
100
N.A.
93.3
93.3
N.A.
N.A.
86.6
6.6
80
N.A.
20
26.6
N.A.
26.6
P-Site Similarity:
100
86.6
100
100
N.A.
93.3
93.3
N.A.
N.A.
100
40
100
N.A.
46.6
53.3
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
20.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
32.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
8
0
0
8
8
0
0
0
0
0
0
% A
% Cys:
0
0
0
77
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
8
0
0
39
0
0
0
0
0
16
0
8
0
% D
% Glu:
8
8
0
0
8
39
77
16
0
0
0
0
16
0
8
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
8
8
0
0
0
0
% G
% His:
0
0
0
0
16
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
0
8
0
70
8
0
0
0
% I
% Lys:
8
8
70
0
0
0
8
0
16
16
0
0
8
0
54
% K
% Leu:
0
0
0
8
0
0
0
0
0
8
0
0
0
85
0
% L
% Met:
0
0
0
0
0
8
0
0
0
31
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
62
16
0
62
0
8
16
62
0
0
8
8
8
8
% Q
% Arg:
70
8
0
0
0
8
0
0
0
0
8
0
0
0
24
% R
% Ser:
0
8
0
8
0
0
0
8
0
8
0
62
70
0
8
% S
% Thr:
0
0
0
0
0
8
0
47
0
24
0
0
0
0
0
% T
% Val:
8
0
0
0
8
0
8
0
8
8
16
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _