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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPS15L1
All Species:
18.48
Human Site:
T217
Identified Species:
33.89
UniProt:
Q9UBC2
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBC2
NP_067058.1
864
94255
T217
P
P
S
K
R
K
K
T
V
F
P
G
A
V
P
Chimpanzee
Pan troglodytes
XP_001139238
933
102460
A208
V
P
M
S
L
P
P
A
L
V
P
P
S
K
R
Rhesus Macaque
Macaca mulatta
XP_001113811
1015
110551
T322
P
P
S
K
R
K
K
T
V
F
P
G
A
V
P
Dog
Lupus familis
XP_541965
908
99427
T217
P
P
S
K
R
K
K
T
V
F
P
G
A
V
P
Cat
Felis silvestris
Mouse
Mus musculus
Q60902
907
99276
T217
P
P
S
K
R
K
K
T
V
F
A
G
A
V
P
Rat
Rattus norvegicus
NP_001025092
878
96428
T217
P
P
S
K
R
K
K
T
V
F
A
G
A
V
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418263
887
97653
P240
P
S
K
R
K
K
T
P
V
F
P
G
A
V
P
Frog
Xenopus laevis
O42287
1270
143652
R311
P
P
S
F
R
R
V
R
S
G
S
G
L
S
I
Zebra Danio
Brachydanio rerio
XP_696575
951
104620
S246
K
R
K
K
S
S
G
S
L
S
S
M
V
P
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_726481
1106
119588
P223
K
P
G
G
A
G
P
P
P
K
P
A
M
P
P
Honey Bee
Apis mellifera
XP_001122937
1043
116535
K208
P
E
L
M
P
P
G
K
R
K
D
S
T
A
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001192039
1179
125310
P305
P
P
S
K
R
K
K
P
A
L
P
G
S
V
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SAT8
1533
164753
N363
P
S
F
A
T
Q
Q
N
T
A
A
V
P
T
I
Conservation
Percent
Protein Identity:
100
44.2
83.9
90.5
N.A.
87.6
88.5
N.A.
N.A.
82
21.1
61.6
N.A.
31.2
34.1
N.A.
32.6
Protein Similarity:
100
61.5
84.1
92.1
N.A.
91.1
91.3
N.A.
N.A.
90.1
36.2
72.9
N.A.
46.4
49.9
N.A.
46.3
P-Site Identity:
100
13.3
100
100
N.A.
93.3
93.3
N.A.
N.A.
60
33.3
6.6
N.A.
20
13.3
N.A.
66.6
P-Site Similarity:
100
26.6
100
100
N.A.
93.3
93.3
N.A.
N.A.
73.3
40
20
N.A.
20
13.3
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
20.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
32.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
8
0
0
8
8
8
24
8
47
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% D
% Glu:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
8
8
0
0
0
0
0
47
0
0
0
0
0
% F
% Gly:
0
0
8
8
0
8
16
0
0
8
0
62
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
16
% I
% Lys:
16
0
16
54
8
54
47
8
0
16
0
0
0
8
0
% K
% Leu:
0
0
8
0
8
0
0
0
16
8
0
0
8
0
0
% L
% Met:
0
0
8
8
0
0
0
0
0
0
0
8
8
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
77
70
0
0
8
16
16
24
8
0
54
8
8
16
62
% P
% Gln:
0
0
0
0
0
8
8
0
0
0
0
0
0
0
0
% Q
% Arg:
0
8
0
8
54
8
0
8
8
0
0
0
0
0
8
% R
% Ser:
0
16
54
8
8
8
0
8
8
8
16
8
16
8
8
% S
% Thr:
0
0
0
0
8
0
8
39
8
0
0
0
8
8
0
% T
% Val:
8
0
0
0
0
0
8
0
47
8
0
8
8
54
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _