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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPS15L1
All Species:
13.64
Human Site:
S535
Identified Species:
25
UniProt:
Q9UBC2
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBC2
NP_067058.1
864
94255
S535
T
I
I
K
S
L
K
S
T
Q
D
E
I
N
Q
Chimpanzee
Pan troglodytes
XP_001139238
933
102460
D521
P
L
Q
Q
H
L
Q
D
S
Q
Q
E
I
S
S
Rhesus Macaque
Macaca mulatta
XP_001113811
1015
110551
S640
T
I
I
K
S
L
K
S
T
Q
D
E
I
N
Q
Dog
Lupus familis
XP_541965
908
99427
S533
T
I
I
K
S
L
K
S
T
Q
D
E
I
N
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q60902
907
99276
C533
T
I
L
R
S
L
K
C
T
Q
D
D
I
N
Q
Rat
Rattus norvegicus
NP_001025092
878
96428
C535
T
I
L
R
S
L
K
C
T
Q
D
D
I
N
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418263
887
97653
S558
T
I
I
K
S
L
K
S
T
Q
E
E
I
N
Q
Frog
Xenopus laevis
O42287
1270
143652
R635
I
K
Q
K
E
L
E
R
K
T
S
E
L
D
K
Zebra Danio
Brachydanio rerio
XP_696575
951
104620
A596
T
I
I
K
S
L
K
A
T
Q
D
E
I
N
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_726481
1106
119588
Q566
S
V
R
S
M
V
T
Q
L
L
E
T
Q
R
Q
Honey Bee
Apis mellifera
XP_001122937
1043
116535
D523
E
L
T
K
N
L
Q
D
T
Q
L
Q
I
C
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001192039
1179
125310
Q633
T
V
E
Q
S
L
N
Q
T
N
Q
E
I
T
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SAT8
1533
164753
A951
D
R
Q
G
G
R
K
A
T
Q
E
P
V
K
A
Conservation
Percent
Protein Identity:
100
44.2
83.9
90.5
N.A.
87.6
88.5
N.A.
N.A.
82
21.1
61.6
N.A.
31.2
34.1
N.A.
32.6
Protein Similarity:
100
61.5
84.1
92.1
N.A.
91.1
91.3
N.A.
N.A.
90.1
36.2
72.9
N.A.
46.4
49.9
N.A.
46.3
P-Site Identity:
100
26.6
100
100
N.A.
73.3
73.3
N.A.
N.A.
93.3
20
93.3
N.A.
6.6
40
N.A.
40
P-Site Similarity:
100
60
100
100
N.A.
93.3
93.3
N.A.
N.A.
100
46.6
100
N.A.
33.3
66.6
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
20.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
32.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
16
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
16
0
0
0
0
0
8
0
% C
% Asp:
8
0
0
0
0
0
0
16
0
0
47
16
0
8
0
% D
% Glu:
8
0
8
0
8
0
8
0
0
0
24
62
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
8
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
54
39
0
0
0
0
0
0
0
0
0
77
0
0
% I
% Lys:
0
8
0
54
0
0
62
0
8
0
0
0
0
8
8
% K
% Leu:
0
16
16
0
0
85
0
0
8
8
8
0
8
0
0
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
8
0
0
8
0
0
0
54
0
% N
% Pro:
8
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% P
% Gln:
0
0
24
16
0
0
16
16
0
77
16
8
8
0
70
% Q
% Arg:
0
8
8
16
0
8
0
8
0
0
0
0
0
8
0
% R
% Ser:
8
0
0
8
62
0
0
31
8
0
8
0
0
8
8
% S
% Thr:
62
0
8
0
0
0
8
0
77
8
0
8
0
8
0
% T
% Val:
0
16
0
0
0
8
0
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _