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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPS15L1
All Species:
26.67
Human Site:
S464
Identified Species:
48.89
UniProt:
Q9UBC2
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBC2
NP_067058.1
864
94255
S464
A
K
L
R
D
M
L
S
D
V
R
Q
K
C
Q
Chimpanzee
Pan troglodytes
XP_001139238
933
102460
K450
A
Q
L
E
E
Q
L
K
E
V
R
K
K
C
A
Rhesus Macaque
Macaca mulatta
XP_001113811
1015
110551
S569
A
K
L
R
D
M
L
S
D
V
R
Q
K
C
Q
Dog
Lupus familis
XP_541965
908
99427
S462
A
K
L
R
D
M
L
S
D
V
R
Q
K
C
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q60902
907
99276
S462
A
K
L
R
D
M
L
S
D
V
R
Q
K
C
Q
Rat
Rattus norvegicus
NP_001025092
878
96428
S464
A
K
L
R
D
M
L
S
D
V
R
Q
K
C
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418263
887
97653
N487
A
K
L
K
D
M
L
N
D
V
R
Q
K
C
Q
Frog
Xenopus laevis
O42287
1270
143652
L564
S
L
H
R
D
S
L
L
T
L
K
R
A
L
E
Zebra Danio
Brachydanio rerio
XP_696575
951
104620
N525
A
K
L
E
D
M
L
N
D
V
R
Q
K
C
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_726481
1106
119588
T495
D
D
L
Q
A
Q
V
T
K
I
R
D
Q
C
H
Honey Bee
Apis mellifera
XP_001122937
1043
116535
S452
A
E
V
D
K
D
L
S
E
I
E
Q
K
I
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001192039
1179
125310
T211
T
K
L
E
G
L
L
T
E
V
Q
S
Q
C
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SAT8
1533
164753
V880
K
E
N
N
E
R
M
V
R
D
V
E
D
S
V
Conservation
Percent
Protein Identity:
100
44.2
83.9
90.5
N.A.
87.6
88.5
N.A.
N.A.
82
21.1
61.6
N.A.
31.2
34.1
N.A.
32.6
Protein Similarity:
100
61.5
84.1
92.1
N.A.
91.1
91.3
N.A.
N.A.
90.1
36.2
72.9
N.A.
46.4
49.9
N.A.
46.3
P-Site Identity:
100
46.6
100
100
N.A.
100
100
N.A.
N.A.
86.6
20
86.6
N.A.
20
33.3
N.A.
40
P-Site Similarity:
100
73.3
100
100
N.A.
100
100
N.A.
N.A.
100
53.3
93.3
N.A.
53.3
60
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
20.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
32.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
70
0
0
0
8
0
0
0
0
0
0
0
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
77
0
% C
% Asp:
8
8
0
8
62
8
0
0
54
8
0
8
8
0
0
% D
% Glu:
0
16
0
24
16
0
0
0
24
0
8
8
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
16
% H
% Ile:
0
0
0
0
0
0
0
0
0
16
0
0
0
8
0
% I
% Lys:
8
62
0
8
8
0
0
8
8
0
8
8
70
0
0
% K
% Leu:
0
8
77
0
0
8
85
8
0
8
0
0
0
8
0
% L
% Met:
0
0
0
0
0
54
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
8
0
0
0
16
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
8
0
16
0
0
0
0
8
62
16
0
62
% Q
% Arg:
0
0
0
47
0
8
0
0
8
0
70
8
0
0
0
% R
% Ser:
8
0
0
0
0
8
0
47
0
0
0
8
0
8
0
% S
% Thr:
8
0
0
0
0
0
0
16
8
0
0
0
0
0
0
% T
% Val:
0
0
8
0
0
0
8
8
0
70
8
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _