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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPS15L1
All Species:
22.73
Human Site:
S390
Identified Species:
41.67
UniProt:
Q9UBC2
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBC2
NP_067058.1
864
94255
S390
V
K
E
L
D
D
I
S
Q
E
I
A
Q
L
Q
Chimpanzee
Pan troglodytes
XP_001139238
933
102460
N376
I
K
E
L
D
T
L
N
N
E
I
V
D
L
Q
Rhesus Macaque
Macaca mulatta
XP_001113811
1015
110551
S495
V
K
E
L
D
D
I
S
Q
E
I
A
Q
L
Q
Dog
Lupus familis
XP_541965
908
99427
S388
V
K
E
L
D
D
I
S
Q
E
I
A
Q
L
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q60902
907
99276
S388
V
K
E
L
D
D
I
S
Q
E
I
A
Q
L
Q
Rat
Rattus norvegicus
NP_001025092
878
96428
S390
V
K
E
L
D
D
I
S
Q
E
I
A
Q
L
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418263
887
97653
S413
V
K
E
L
D
D
I
S
Q
E
I
A
Q
L
Q
Frog
Xenopus laevis
O42287
1270
143652
R498
E
G
K
L
Q
D
I
R
C
R
L
T
T
Q
R
Zebra Danio
Brachydanio rerio
XP_696575
951
104620
R419
A
A
L
T
E
M
R
R
D
S
S
S
S
V
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_726481
1106
119588
K429
P
E
L
E
M
I
S
K
E
I
E
E
L
A
R
Honey Bee
Apis mellifera
XP_001122937
1043
116535
I378
L
D
M
I
S
K
D
I
A
E
L
V
K
E
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001192039
1179
125310
I130
A
P
G
D
F
S
A
I
K
E
L
D
A
I
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SAT8
1533
164753
L628
R
K
N
T
G
A
S
L
L
P
Q
K
T
G
V
Conservation
Percent
Protein Identity:
100
44.2
83.9
90.5
N.A.
87.6
88.5
N.A.
N.A.
82
21.1
61.6
N.A.
31.2
34.1
N.A.
32.6
Protein Similarity:
100
61.5
84.1
92.1
N.A.
91.1
91.3
N.A.
N.A.
90.1
36.2
72.9
N.A.
46.4
49.9
N.A.
46.3
P-Site Identity:
100
53.3
100
100
N.A.
100
100
N.A.
N.A.
100
20
0
N.A.
0
6.6
N.A.
6.6
P-Site Similarity:
100
73.3
100
100
N.A.
100
100
N.A.
N.A.
100
40
20
N.A.
20
40
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
20.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
32.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
8
0
0
0
8
8
0
8
0
0
47
8
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
0
8
0
8
54
54
8
0
8
0
0
8
8
0
0
% D
% Glu:
8
8
54
8
8
0
0
0
8
70
8
8
0
8
0
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
8
0
8
0
0
0
0
0
0
0
0
8
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
8
0
8
54
16
0
8
54
0
0
8
0
% I
% Lys:
0
62
8
0
0
8
0
8
8
0
0
8
8
0
0
% K
% Leu:
8
0
16
62
0
0
8
8
8
0
24
0
8
54
0
% L
% Met:
0
0
8
0
8
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
0
8
8
0
0
0
0
0
0
% N
% Pro:
8
8
0
0
0
0
0
0
0
8
0
0
0
0
0
% P
% Gln:
0
0
0
0
8
0
0
0
47
0
8
0
47
8
54
% Q
% Arg:
8
0
0
0
0
0
8
16
0
8
0
0
0
0
24
% R
% Ser:
0
0
0
0
8
8
16
47
0
8
8
8
8
0
8
% S
% Thr:
0
0
0
16
0
8
0
0
0
0
0
8
16
0
0
% T
% Val:
47
0
0
0
0
0
0
0
0
0
0
16
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _