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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPS15L1
All Species:
15.45
Human Site:
S374
Identified Species:
28.33
UniProt:
Q9UBC2
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBC2
NP_067058.1
864
94255
S374
P
G
P
D
S
S
G
S
L
G
S
G
E
F
T
Chimpanzee
Pan troglodytes
XP_001139238
933
102460
S360
L
Q
K
N
I
I
G
S
S
P
V
A
D
F
S
Rhesus Macaque
Macaca mulatta
XP_001113811
1015
110551
S479
P
G
P
D
S
S
G
S
L
G
S
G
E
F
T
Dog
Lupus familis
XP_541965
908
99427
C372
P
I
P
D
G
S
S
C
L
G
S
G
E
F
T
Cat
Felis silvestris
Mouse
Mus musculus
Q60902
907
99276
T372
P
I
P
D
S
S
S
T
L
A
S
G
E
F
T
Rat
Rattus norvegicus
NP_001025092
878
96428
A374
P
I
P
D
S
S
S
A
L
G
S
G
E
F
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418263
887
97653
S397
P
I
Q
D
S
S
S
S
V
G
S
G
E
F
T
Frog
Xenopus laevis
O42287
1270
143652
A482
T
L
E
F
E
L
E
A
L
N
D
K
K
H
Q
Zebra Danio
Brachydanio rerio
XP_696575
951
104620
Y403
P
G
P
S
L
S
G
Y
M
T
P
V
G
S
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_726481
1106
119588
Q413
A
G
V
D
L
Q
P
Q
E
V
K
P
T
Y
S
Honey Bee
Apis mellifera
XP_001122937
1043
116535
N362
E
S
I
V
E
N
N
N
I
S
G
Y
S
N
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001192039
1179
125310
A114
G
G
T
E
P
G
L
A
E
L
G
S
I
P
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SAT8
1533
164753
N612
A
S
I
G
M
V
K
N
M
L
H
Q
E
S
E
Conservation
Percent
Protein Identity:
100
44.2
83.9
90.5
N.A.
87.6
88.5
N.A.
N.A.
82
21.1
61.6
N.A.
31.2
34.1
N.A.
32.6
Protein Similarity:
100
61.5
84.1
92.1
N.A.
91.1
91.3
N.A.
N.A.
90.1
36.2
72.9
N.A.
46.4
49.9
N.A.
46.3
P-Site Identity:
100
20
100
73.3
N.A.
73.3
80
N.A.
N.A.
73.3
6.6
33.3
N.A.
13.3
0
N.A.
6.6
P-Site Similarity:
100
40
100
73.3
N.A.
80
86.6
N.A.
N.A.
80
20
40
N.A.
26.6
20
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
20.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
32.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
0
0
0
0
0
24
0
8
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
54
0
0
0
0
0
0
8
0
8
0
8
% D
% Glu:
8
0
8
8
16
0
8
0
16
0
0
0
54
0
8
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
0
0
0
54
0
% F
% Gly:
8
39
0
8
8
8
31
0
0
39
16
47
8
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
0
0
8
0
% H
% Ile:
0
31
16
0
8
8
0
0
8
0
0
0
8
0
0
% I
% Lys:
0
0
8
0
0
0
8
0
0
0
8
8
8
0
0
% K
% Leu:
8
8
0
0
16
8
8
0
47
16
0
0
0
0
0
% L
% Met:
0
0
0
0
8
0
0
0
16
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
8
8
16
0
8
0
0
0
8
0
% N
% Pro:
54
0
47
0
8
0
8
0
0
8
8
8
0
8
8
% P
% Gln:
0
8
8
0
0
8
0
8
0
0
0
8
0
0
8
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
16
0
8
39
54
31
31
8
8
47
8
8
16
16
% S
% Thr:
8
0
8
0
0
0
0
8
0
8
0
0
8
0
47
% T
% Val:
0
0
8
8
0
8
0
0
8
8
8
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
8
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _