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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPS15L1
All Species:
28.48
Human Site:
S241
Identified Species:
52.22
UniProt:
Q9UBC2
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBC2
NP_067058.1
864
94255
S241
D
S
L
R
S
T
P
S
H
G
S
V
S
S
L
Chimpanzee
Pan troglodytes
XP_001139238
933
102460
S232
R
L
I
P
S
S
A
S
A
K
E
S
Y
H
S
Rhesus Macaque
Macaca mulatta
XP_001113811
1015
110551
S346
D
S
L
R
S
T
P
S
H
G
S
V
S
S
L
Dog
Lupus familis
XP_541965
908
99427
S241
D
S
L
R
S
T
P
S
H
G
S
V
S
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q60902
907
99276
S241
D
S
L
R
S
T
P
S
H
G
S
V
S
S
L
Rat
Rattus norvegicus
NP_001025092
878
96428
S241
D
S
L
R
S
T
P
S
H
G
S
V
S
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418263
887
97653
S264
D
S
L
R
S
T
P
S
H
G
S
V
N
S
L
Frog
Xenopus laevis
O42287
1270
143652
E335
L
P
E
E
P
E
E
E
E
P
Q
N
A
D
K
Zebra Danio
Brachydanio rerio
XP_696575
951
104620
S270
D
S
L
R
S
T
P
S
H
G
S
M
N
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_726481
1106
119588
G247
A
P
S
G
E
G
F
G
D
G
G
F
V
A
N
Honey Bee
Apis mellifera
XP_001122937
1043
116535
P232
V
I
T
T
V
P
P
P
I
P
P
L
P
N
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001192039
1179
125310
P329
A
L
R
R
V
T
P
P
P
T
S
P
A
L
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SAT8
1533
164753
M387
S
A
I
L
Q
A
Q
M
T
G
F
P
A
Q
Q
Conservation
Percent
Protein Identity:
100
44.2
83.9
90.5
N.A.
87.6
88.5
N.A.
N.A.
82
21.1
61.6
N.A.
31.2
34.1
N.A.
32.6
Protein Similarity:
100
61.5
84.1
92.1
N.A.
91.1
91.3
N.A.
N.A.
90.1
36.2
72.9
N.A.
46.4
49.9
N.A.
46.3
P-Site Identity:
100
13.3
100
100
N.A.
100
100
N.A.
N.A.
93.3
0
86.6
N.A.
6.6
6.6
N.A.
26.6
P-Site Similarity:
100
26.6
100
100
N.A.
100
100
N.A.
N.A.
100
6.6
100
N.A.
13.3
26.6
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
20.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
32.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
8
0
0
0
8
8
0
8
0
0
0
24
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
54
0
0
0
0
0
0
0
8
0
0
0
0
8
0
% D
% Glu:
0
0
8
8
8
8
8
8
8
0
8
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
8
8
0
0
0
% F
% Gly:
0
0
0
8
0
8
0
8
0
70
8
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
54
0
0
0
0
8
0
% H
% Ile:
0
8
16
0
0
0
0
0
8
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
8
% K
% Leu:
8
16
54
8
0
0
0
0
0
0
0
8
0
8
54
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
8
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
8
16
8
8
% N
% Pro:
0
16
0
8
8
8
70
16
8
16
8
16
8
0
0
% P
% Gln:
0
0
0
0
8
0
8
0
0
0
8
0
0
8
8
% Q
% Arg:
8
0
8
62
0
0
0
0
0
0
0
0
0
0
8
% R
% Ser:
8
54
8
0
62
8
0
62
0
0
62
8
39
54
8
% S
% Thr:
0
0
8
8
0
62
0
0
8
8
0
0
0
0
0
% T
% Val:
8
0
0
0
16
0
0
0
0
0
0
47
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _