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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STX18
All Species:
31.21
Human Site:
T271
Identified Species:
52.82
UniProt:
Q9P2W9
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P2W9
NP_058626.1
335
38674
T271
S
R
L
Q
E
I
F
T
E
K
V
L
Q
Q
E
Chimpanzee
Pan troglodytes
XP_001154387
335
38724
T271
S
R
L
Q
E
I
F
T
E
K
V
L
Q
Q
E
Rhesus Macaque
Macaca mulatta
XP_001094903
335
38636
T271
S
R
L
Q
E
I
F
T
E
K
V
L
Q
Q
E
Dog
Lupus familis
XP_851021
336
38679
T272
S
R
L
Q
E
I
F
T
E
K
V
L
Q
Q
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8VDS8
334
38363
T270
S
R
L
Q
E
I
F
T
E
K
V
L
Q
Q
E
Rat
Rattus norvegicus
Q68FW4
334
38494
T270
S
R
L
Q
E
I
F
T
E
K
V
L
Q
Q
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001089679
372
42507
T265
S
R
L
Q
E
I
F
T
E
K
V
L
Q
Q
E
Zebra Danio
Brachydanio rerio
Q4VBI7
314
36223
H264
E
T
E
I
D
S
I
H
Q
L
V
V
G
A
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524485
395
45117
T331
A
Q
L
Q
D
I
F
T
E
K
V
A
M
Q
Q
Honey Bee
Apis mellifera
XP_623865
296
34345
V250
D
R
L
M
T
T
V
V
G
S
T
E
N
V
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782212
312
36043
G263
S
A
D
I
D
R
I
G
D
T
V
V
H
T
T
Poplar Tree
Populus trichocarpa
XP_002316241
311
35519
E263
Q
Q
I
E
L
L
Y
E
Q
A
V
E
A
T
K
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P59277
310
35555
A264
I
E
F
L
Y
D
Q
A
V
E
A
T
K
N
V
Baker's Yeast
Sacchar. cerevisiae
P36116
164
18893
N118
L
G
K
E
T
E
T
N
N
S
I
K
N
T
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99.6
95.2
N.A.
92.5
92.8
N.A.
N.A.
N.A.
62.6
70.4
N.A.
32.4
46.8
N.A.
48.9
Protein Similarity:
100
99.6
99.6
97.9
N.A.
96.1
96.1
N.A.
N.A.
N.A.
71.5
80.3
N.A.
51.9
66.2
N.A.
64.1
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
N.A.
100
6.6
N.A.
60
13.3
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
N.A.
100
26.6
N.A.
86.6
20
N.A.
33.3
Percent
Protein Identity:
25
N.A.
N.A.
24.1
20.9
N.A.
Protein Similarity:
46.2
N.A.
N.A.
47.7
32.8
N.A.
P-Site Identity:
6.6
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
53.3
N.A.
N.A.
13.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
0
0
0
8
0
8
8
8
8
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
8
0
22
8
0
0
8
0
0
0
0
0
0
% D
% Glu:
8
8
8
15
50
8
0
8
58
8
0
15
0
0
50
% E
% Phe:
0
0
8
0
0
0
58
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
0
0
0
0
8
8
0
0
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
0
% H
% Ile:
8
0
8
15
0
58
15
0
0
0
8
0
0
0
8
% I
% Lys:
0
0
8
0
0
0
0
0
0
58
0
8
8
0
15
% K
% Leu:
8
0
65
8
8
8
0
0
0
8
0
50
0
0
0
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
8
0
0
0
15
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
15
0
58
0
0
8
0
15
0
0
0
50
58
8
% Q
% Arg:
0
58
0
0
0
8
0
0
0
0
0
0
0
0
0
% R
% Ser:
58
0
0
0
0
8
0
0
0
15
0
0
0
0
0
% S
% Thr:
0
8
0
0
15
8
8
58
0
8
8
8
0
22
15
% T
% Val:
0
0
0
0
0
0
8
8
8
0
79
15
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _