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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STX18
All Species:
13.64
Human Site:
S167
Identified Species:
23.08
UniProt:
Q9P2W9
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P2W9
NP_058626.1
335
38674
S167
V
V
D
K
K
R
L
S
K
L
E
P
E
P
N
Chimpanzee
Pan troglodytes
XP_001154387
335
38724
S167
V
V
D
K
K
R
L
S
K
L
E
P
E
P
N
Rhesus Macaque
Macaca mulatta
XP_001094903
335
38636
S167
V
V
D
K
K
R
L
S
K
L
E
P
E
P
N
Dog
Lupus familis
XP_851021
336
38679
S168
V
V
D
K
K
R
L
S
K
L
E
P
E
P
H
Cat
Felis silvestris
Mouse
Mus musculus
Q8VDS8
334
38363
L166
R
V
V
D
K
K
R
L
S
K
L
E
P
E
P
Rat
Rattus norvegicus
Q68FW4
334
38494
L166
R
V
V
D
K
K
R
L
S
K
L
E
P
E
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001089679
372
42507
K166
L
S
R
L
E
P
E
K
I
N
K
T
Q
S
S
Zebra Danio
Brachydanio rerio
Q4VBI7
314
36223
L165
R
V
V
D
K
K
R
L
S
R
L
E
P
E
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524485
395
45117
G227
D
W
D
E
D
E
E
G
D
E
V
D
D
H
D
Honey Bee
Apis mellifera
XP_623865
296
34345
I152
R
V
K
R
A
M
E
I
R
K
I
A
K
L
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782212
312
36043
L164
D
K
K
R
I
S
R
L
R
Q
D
G
P
S
S
Poplar Tree
Populus trichocarpa
XP_002316241
311
35519
N165
I
R
F
Q
D
A
I
N
K
R
I
P
R
R
K
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P59277
310
35555
N165
T
R
F
Q
D
I
I
N
R
A
M
P
R
R
K
Baker's Yeast
Sacchar. cerevisiae
P36116
164
18893
R20
V
S
S
L
N
K
D
R
R
L
L
L
R
E
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99.6
95.2
N.A.
92.5
92.8
N.A.
N.A.
N.A.
62.6
70.4
N.A.
32.4
46.8
N.A.
48.9
Protein Similarity:
100
99.6
99.6
97.9
N.A.
96.1
96.1
N.A.
N.A.
N.A.
71.5
80.3
N.A.
51.9
66.2
N.A.
64.1
P-Site Identity:
100
100
100
93.3
N.A.
13.3
13.3
N.A.
N.A.
N.A.
0
13.3
N.A.
6.6
6.6
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
20
20
N.A.
N.A.
N.A.
33.3
20
N.A.
26.6
26.6
N.A.
26.6
Percent
Protein Identity:
25
N.A.
N.A.
24.1
20.9
N.A.
Protein Similarity:
46.2
N.A.
N.A.
47.7
32.8
N.A.
P-Site Identity:
13.3
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
40
N.A.
N.A.
33.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
8
0
0
0
8
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
15
0
36
22
22
0
8
0
8
0
8
8
8
0
8
% D
% Glu:
0
0
0
8
8
8
22
0
0
8
29
22
29
29
8
% E
% Phe:
0
0
15
0
0
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
0
0
0
0
0
0
0
8
0
0
0
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% H
% Ile:
8
0
0
0
8
8
15
8
8
0
15
0
0
0
0
% I
% Lys:
0
8
15
29
50
29
0
8
36
22
8
0
8
0
15
% K
% Leu:
8
0
0
15
0
0
29
29
0
36
29
8
0
8
0
% L
% Met:
0
0
0
0
0
8
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
15
0
8
0
0
0
0
22
% N
% Pro:
0
0
0
0
0
8
0
0
0
0
0
43
29
29
15
% P
% Gln:
0
0
0
15
0
0
0
0
0
8
0
0
8
0
8
% Q
% Arg:
29
15
8
15
0
29
29
8
29
15
0
0
22
15
0
% R
% Ser:
0
15
8
0
0
8
0
29
22
0
0
0
0
15
15
% S
% Thr:
8
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% T
% Val:
36
58
22
0
0
0
0
0
0
0
8
0
0
0
0
% V
% Trp:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _