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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR8
All Species:
26.97
Human Site:
T176
Identified Species:
59.33
UniProt:
Q9P2S5
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P2S5
NP_060288.3
460
51588
T176
Q
L
L
R
H
F
D
T
D
T
Q
D
L
T
G
Chimpanzee
Pan troglodytes
XP_001151905
460
51641
T176
Q
L
L
R
H
F
D
T
D
T
Q
D
L
T
G
Rhesus Macaque
Macaca mulatta
XP_001084011
461
51534
T176
Q
L
L
R
H
F
D
T
D
T
Q
D
L
T
G
Dog
Lupus familis
XP_536722
460
51757
T176
Q
L
L
R
H
F
D
T
E
T
Q
D
L
A
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9JM98
462
52008
T176
Q
L
L
R
H
F
D
T
D
T
Q
D
L
T
G
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506726
450
50849
T176
Q
L
L
R
H
F
D
T
D
T
Q
D
L
A
G
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6GMD2
305
33316
S37
D
G
S
E
L
V
I
S
G
S
L
D
D
L
V
Zebra Danio
Brachydanio rerio
NP_956187
446
50971
S176
H
L
L
R
H
F
E
S
E
T
Q
D
L
A
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001193137
396
44809
D130
Q
G
M
H
F
T
K
D
G
K
Y
M
A
L
A
Poplar Tree
Populus trichocarpa
XP_002297923
338
38049
I72
W
S
P
D
D
S
A
I
V
I
W
D
A
P
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O22785
525
56709
Q198
R
K
K
R
Q
I
P
Q
T
L
A
S
I
D
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
93.4
89.7
N.A.
88.3
N.A.
N.A.
83.4
N.A.
20
70.2
N.A.
N.A.
N.A.
N.A.
54.5
Protein Similarity:
100
99.3
94.3
95.2
N.A.
93.7
N.A.
N.A.
91
N.A.
37.1
81
N.A.
N.A.
N.A.
N.A.
69.5
P-Site Identity:
100
100
100
86.6
N.A.
100
N.A.
N.A.
93.3
N.A.
6.6
66.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
100
N.A.
N.A.
93.3
N.A.
20
86.6
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
33
N.A.
N.A.
20.5
N.A.
N.A.
Protein Similarity:
45.2
N.A.
N.A.
33.7
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
6.6
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
0
0
0
10
0
19
28
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
10
10
0
55
10
46
0
0
82
10
10
0
% D
% Glu:
0
0
0
10
0
0
10
0
19
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
10
64
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
19
0
0
0
0
0
0
19
0
0
0
0
0
64
% G
% His:
10
0
0
10
64
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
10
10
10
0
10
0
0
10
0
0
% I
% Lys:
0
10
10
0
0
0
10
0
0
10
0
0
0
0
0
% K
% Leu:
0
64
64
0
10
0
0
0
0
10
10
0
64
19
10
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
10
0
0
0
10
0
0
0
0
0
0
10
0
% P
% Gln:
64
0
0
0
10
0
0
10
0
0
64
0
0
0
0
% Q
% Arg:
10
0
0
73
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
10
10
0
0
10
0
19
0
10
0
10
0
0
0
% S
% Thr:
0
0
0
0
0
10
0
55
10
64
0
0
0
37
10
% T
% Val:
0
0
0
0
0
10
0
0
10
0
0
0
0
0
10
% V
% Trp:
10
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _