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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WDR8 All Species: 14.85
Human Site: S218 Identified Species: 32.67
UniProt: Q9P2S5 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P2S5 NP_060288.3 460 51588 S218 G R L L S T Y S A Y E W S L G
Chimpanzee Pan troglodytes XP_001151905 460 51641 S218 G R L L S T Y S A Y E W S L G
Rhesus Macaque Macaca mulatta XP_001084011 461 51534 S218 G R L L S A Y S A Y E W S L G
Dog Lupus familis XP_536722 460 51757 C218 G R L L S A Y C A Y E W S L G
Cat Felis silvestris
Mouse Mus musculus Q9JM98 462 52008 C218 G R L L S A Y C A Y E W S L G
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506726 450 50849 C218 G R L L S T Y C A Y E W S L G
Chicken Gallus gallus
Frog Xenopus laevis Q6GMD2 305 33316 M79 V S P S G N I M A S S S L D A
Zebra Danio Brachydanio rerio NP_956187 446 50971 S218 G R L L S F Y S A Y E W S L G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001193137 396 44809 E171 T R D L A G L E W S P D G R V
Poplar Tree Populus trichocarpa XP_002297923 338 38049 C113 K S V S W S P C G Q Y L A V G
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O22785 525 56709 S283 S D L V L T A S A D K T V R I
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 93.4 89.7 N.A. 88.3 N.A. N.A. 83.4 N.A. 20 70.2 N.A. N.A. N.A. N.A. 54.5
Protein Similarity: 100 99.3 94.3 95.2 N.A. 93.7 N.A. N.A. 91 N.A. 37.1 81 N.A. N.A. N.A. N.A. 69.5
P-Site Identity: 100 100 93.3 86.6 N.A. 86.6 N.A. N.A. 93.3 N.A. 6.6 93.3 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 100 93.3 86.6 N.A. 86.6 N.A. N.A. 93.3 N.A. 6.6 93.3 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: 33 N.A. N.A. 20.5 N.A. N.A.
Protein Similarity: 45.2 N.A. N.A. 33.7 N.A. N.A.
P-Site Identity: 6.6 N.A. N.A. 26.6 N.A. N.A.
P-Site Similarity: 33.3 N.A. N.A. 40 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 10 28 10 0 82 0 0 0 10 0 10 % A
% Cys: 0 0 0 0 0 0 0 37 0 0 0 0 0 0 0 % C
% Asp: 0 10 10 0 0 0 0 0 0 10 0 10 0 10 0 % D
% Glu: 0 0 0 0 0 0 0 10 0 0 64 0 0 0 0 % E
% Phe: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % F
% Gly: 64 0 0 0 10 10 0 0 10 0 0 0 10 0 73 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 10 % I
% Lys: 10 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % K
% Leu: 0 0 73 73 10 0 10 0 0 0 0 10 10 64 0 % L
% Met: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 10 0 0 0 10 0 0 0 10 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % Q
% Arg: 0 73 0 0 0 0 0 0 0 0 0 0 0 19 0 % R
% Ser: 10 19 0 19 64 10 0 46 0 19 10 10 64 0 0 % S
% Thr: 10 0 0 0 0 37 0 0 0 0 0 10 0 0 0 % T
% Val: 10 0 10 10 0 0 0 0 0 0 0 0 10 10 10 % V
% Trp: 0 0 0 0 10 0 0 0 10 0 0 64 0 0 0 % W
% Tyr: 0 0 0 0 0 0 64 0 0 64 10 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _