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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LARS All Species: 33.94
Human Site: S879 Identified Species: 62.22
UniProt: Q9P2J5 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P2J5 NP_064502.9 1176 134466 S879 T L L G K P D S I M N A S W P
Chimpanzee Pan troglodytes XP_001157096 1176 134469 S879 T L L G K P D S I M N A S W P
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_535229 1176 134216 S879 T L L G K P D S I M N A S W P
Cat Felis silvestris
Mouse Mus musculus Q8BMJ2 1178 134174 S881 T L L G K P D S I M H A S W P
Rat Rattus norvegicus NP_001009637 1178 134260 S881 T L L G K P D S I M H A S W P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_414663 1177 134257 S880 S L L G K P D S I M K A S W P
Frog Xenopus laevis NP_001087393 1178 134087 S881 S L L G K T G S L M Q A S W P
Zebra Danio Brachydanio rerio XP_698279 747 84899 K504 G D N K P P A K P T H C T I Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_787968 1182 134854 S881 G L L G N K E S I V H A R W P
Honey Bee Apis mellifera XP_395743 1181 136743 S878 T L I G K E G S I L N A R W P
Nematode Worm Caenorhab. elegans Q09996 1186 134501 L885 Q L L G K D G L I V N A P W P
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P26637 1090 124123 Y846 D F Q A A R D Y Y R E A S G V
Red Bread Mold Neurospora crassa P10857 1123 126381 R876 L N A R D M Y R E A C A A A G
Conservation
Percent
Protein Identity: 100 99.5 N.A. 94.9 N.A. 90 89.9 N.A. N.A. 87 82.5 50.5 N.A. 59.3 60.9 56.6 N.A.
Protein Similarity: 100 99.9 N.A. 97.5 N.A. 96.1 96 N.A. N.A. 93.5 92.6 57.4 N.A. 75.3 78.2 71.4 N.A.
P-Site Identity: 100 100 N.A. 100 N.A. 93.3 93.3 N.A. N.A. 86.6 66.6 6.6 N.A. 53.3 66.6 60 N.A.
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. N.A. 93.3 80 20 N.A. 73.3 80 66.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 43.7 43.8
Protein Similarity: N.A. N.A. N.A. N.A. 61.1 61.6
P-Site Identity: N.A. N.A. N.A. N.A. 20 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. 20 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 8 8 0 8 0 0 8 0 93 8 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 8 8 0 0 0 % C
% Asp: 8 8 0 0 8 8 54 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 8 8 0 8 0 8 0 0 0 0 % E
% Phe: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 16 0 0 77 0 0 24 0 0 0 0 0 0 8 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 31 0 0 0 0 % H
% Ile: 0 0 8 0 0 0 0 0 70 0 0 0 0 8 0 % I
% Lys: 0 0 0 8 70 8 0 8 0 0 8 0 0 0 0 % K
% Leu: 8 77 70 0 0 0 0 8 8 8 0 0 0 0 0 % L
% Met: 0 0 0 0 0 8 0 0 0 54 0 0 0 0 0 % M
% Asn: 0 8 8 0 8 0 0 0 0 0 39 0 0 0 0 % N
% Pro: 0 0 0 0 8 54 0 0 8 0 0 0 8 0 77 % P
% Gln: 8 0 8 0 0 0 0 0 0 0 8 0 0 0 0 % Q
% Arg: 0 0 0 8 0 8 0 8 0 8 0 0 16 0 0 % R
% Ser: 16 0 0 0 0 0 0 70 0 0 0 0 62 0 0 % S
% Thr: 47 0 0 0 0 8 0 0 0 8 0 0 8 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 16 0 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 77 0 % W
% Tyr: 0 0 0 0 0 0 8 8 8 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _