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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LARS
All Species:
24.55
Human Site:
S621
Identified Species:
45
UniProt:
Q9P2J5
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P2J5
NP_064502.9
1176
134466
S621
N
L
H
G
Q
A
E
S
P
L
G
I
R
P
Q
Chimpanzee
Pan troglodytes
XP_001157096
1176
134469
S621
N
L
H
G
Q
A
E
S
P
L
G
I
R
P
Q
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_535229
1176
134216
S621
N
L
R
G
Q
T
E
S
P
L
G
I
R
P
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8BMJ2
1178
134174
S623
D
L
N
G
Q
A
E
S
P
L
G
I
R
P
Q
Rat
Rattus norvegicus
NP_001009637
1178
134260
S623
D
L
Q
G
Q
A
E
S
P
L
G
I
R
P
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414663
1177
134257
S622
N
L
R
G
Q
G
E
S
P
L
G
I
R
A
H
Frog
Xenopus laevis
NP_001087393
1178
134087
S623
D
L
S
G
Q
G
E
S
P
L
G
I
R
P
E
Zebra Danio
Brachydanio rerio
XP_698279
747
84899
N260
H
L
S
Y
Y
L
Y
N
H
V
A
M
W
P
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_787968
1182
134854
G621
T
F
R
G
E
K
P
G
P
F
G
I
K
P
S
Honey Bee
Apis mellifera
XP_395743
1181
136743
N619
T
F
K
G
D
K
P
N
T
Y
N
I
K
P
D
Nematode Worm
Caenorhab. elegans
Q09996
1186
134501
G622
A
F
D
G
S
V
V
G
P
A
G
I
K
A
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P26637
1090
124123
D602
L
G
T
R
L
P
W
D
E
K
Y
L
V
E
S
Red Bread Mold
Neurospora crassa
P10857
1123
126381
L630
L
P
W
D
P
N
F
L
V
E
S
L
S
D
S
Conservation
Percent
Protein Identity:
100
99.5
N.A.
94.9
N.A.
90
89.9
N.A.
N.A.
87
82.5
50.5
N.A.
59.3
60.9
56.6
N.A.
Protein Similarity:
100
99.9
N.A.
97.5
N.A.
96.1
96
N.A.
N.A.
93.5
92.6
57.4
N.A.
75.3
78.2
71.4
N.A.
P-Site Identity:
100
100
N.A.
86.6
N.A.
86.6
86.6
N.A.
N.A.
73.3
73.3
13.3
N.A.
33.3
20
26.6
N.A.
P-Site Similarity:
100
100
N.A.
86.6
N.A.
100
93.3
N.A.
N.A.
73.3
86.6
40
N.A.
46.6
33.3
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
43.7
43.8
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
61.1
61.6
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
31
0
0
0
8
8
0
0
16
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
24
0
8
8
8
0
0
8
0
0
0
0
0
8
16
% D
% Glu:
0
0
0
0
8
0
54
0
8
8
0
0
0
8
8
% E
% Phe:
0
24
0
0
0
0
8
0
0
8
0
0
0
0
0
% F
% Gly:
0
8
0
77
0
16
0
16
0
0
70
0
0
0
0
% G
% His:
8
0
16
0
0
0
0
0
8
0
0
0
0
0
8
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
77
0
0
0
% I
% Lys:
0
0
8
0
0
16
0
0
0
8
0
0
24
0
0
% K
% Leu:
16
62
0
0
8
8
0
8
0
54
0
16
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
31
0
8
0
0
8
0
16
0
0
8
0
0
0
8
% N
% Pro:
0
8
0
0
8
8
16
0
70
0
0
0
0
70
0
% P
% Gln:
0
0
8
0
54
0
0
0
0
0
0
0
0
0
39
% Q
% Arg:
0
0
24
8
0
0
0
0
0
0
0
0
54
0
0
% R
% Ser:
0
0
16
0
8
0
0
54
0
0
8
0
8
0
24
% S
% Thr:
16
0
8
0
0
8
0
0
8
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
8
8
0
8
8
0
0
8
0
0
% V
% Trp:
0
0
8
0
0
0
8
0
0
0
0
0
8
0
0
% W
% Tyr:
0
0
0
8
8
0
8
0
0
8
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _