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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CPSF2
All Species:
35.76
Human Site:
Y395
Identified Species:
52.44
UniProt:
Q9P2I0
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P2I0
NP_059133.1
782
88487
Y395
E
G
K
E
L
E
E
Y
L
E
K
E
K
L
K
Chimpanzee
Pan troglodytes
XP_001147204
731
82848
R384
T
E
I
E
L
R
K
R
V
K
L
E
G
K
E
Rhesus Macaque
Macaca mulatta
XP_001092942
782
88454
Y395
E
G
K
E
L
E
E
Y
L
E
K
E
K
L
K
Dog
Lupus familis
XP_537353
782
88470
Y395
E
G
K
E
L
E
E
Y
L
E
K
E
K
L
K
Cat
Felis silvestris
Mouse
Mus musculus
O35218
782
88364
Y395
E
G
K
E
L
E
E
Y
V
E
K
E
K
L
K
Rat
Rattus norvegicus
Q3MHC2
600
67822
T254
E
L
C
I
L
L
E
T
F
W
E
R
M
N
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507374
782
88381
Y395
E
G
K
E
L
E
E
Y
L
E
K
E
K
L
K
Chicken
Gallus gallus
Q5ZIH0
600
68170
T254
E
L
C
I
L
L
E
T
F
W
E
R
M
N
L
Frog
Xenopus laevis
Q9W799
783
88968
Y395
E
G
K
E
L
E
E
Y
V
E
K
E
K
L
K
Zebra Danio
Brachydanio rerio
NP_001002384
790
89603
Y395
E
G
R
E
L
E
E
Y
M
E
K
E
R
M
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3D6
756
85400
E393
R
V
D
L
E
G
A
E
L
E
E
Y
L
R
T
Honey Bee
Apis mellifera
XP_394940
737
83538
G389
K
R
R
I
K
L
E
G
L
E
L
E
E
Y
Q
Nematode Worm
Caenorhab. elegans
O17403
843
95598
Y405
E
G
E
E
L
L
E
Y
K
R
R
K
A
E
R
Sea Urchin
Strong. purpuratus
XP_780045
776
88380
Y395
E
K
E
E
L
D
E
Y
R
I
H
E
K
E
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LKF9
739
82121
L390
V
P
L
A
G
E
E
L
I
A
Y
E
E
E
Q
Baker's Yeast
Sacchar. cerevisiae
Q06224
779
87655
A406
Q
V
E
E
I
S
F
A
A
H
V
D
F
Q
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.4
99.8
99.6
N.A.
97.9
23.6
N.A.
98.4
23.6
91.3
86
N.A.
56
59.5
42.4
61.1
Protein Similarity:
100
93.4
100
99.8
N.A.
99.6
39.7
N.A.
99.4
40
96.8
93.1
N.A.
72.1
76.5
63.9
77.2
P-Site Identity:
100
20
100
100
N.A.
93.3
20
N.A.
100
20
93.3
73.3
N.A.
13.3
26.6
40
53.3
P-Site Similarity:
100
46.6
100
100
N.A.
100
26.6
N.A.
100
26.6
100
100
N.A.
20
53.3
66.6
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.4
20
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
57.4
41.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
0
0
7
7
7
7
0
0
7
0
0
% A
% Cys:
0
0
13
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
7
0
0
7
0
0
0
0
0
7
0
0
0
% D
% Glu:
69
7
19
69
7
50
82
7
0
57
19
69
13
19
13
% E
% Phe:
0
0
0
0
0
0
7
0
13
0
0
0
7
0
0
% F
% Gly:
0
50
0
0
7
7
0
7
0
0
0
0
7
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
7
7
0
0
0
0
% H
% Ile:
0
0
7
19
7
0
0
0
7
7
0
0
0
0
0
% I
% Lys:
7
7
38
0
7
0
7
0
7
7
44
7
44
7
50
% K
% Leu:
0
13
7
7
75
25
0
7
38
0
13
0
7
38
13
% L
% Met:
0
0
0
0
0
0
0
0
7
0
0
0
13
7
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
0
% N
% Pro:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
7
0
0
0
0
0
0
0
0
0
0
0
0
7
13
% Q
% Arg:
7
7
13
0
0
7
0
7
7
7
7
13
7
7
7
% R
% Ser:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% S
% Thr:
7
0
0
0
0
0
0
13
0
0
0
0
0
0
7
% T
% Val:
7
13
0
0
0
0
0
0
19
0
7
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
57
0
0
7
7
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _