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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CPSF2
All Species:
27.58
Human Site:
S452
Identified Species:
40.44
UniProt:
Q9P2I0
Number Species:
15
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P2I0
NP_059133.1
782
88487
S452
G
E
G
S
R
K
G
S
F
F
K
Q
A
K
K
Chimpanzee
Pan troglodytes
XP_001147204
731
82848
H439
P
S
A
H
K
T
K
H
D
L
M
M
K
G
E
Rhesus Macaque
Macaca mulatta
XP_001092942
782
88454
S452
G
E
G
S
R
K
G
S
F
F
K
Q
A
K
K
Dog
Lupus familis
XP_537353
782
88470
S452
G
E
G
S
R
K
G
S
F
F
K
Q
A
K
K
Cat
Felis silvestris
Mouse
Mus musculus
O35218
782
88364
S452
G
E
G
S
R
K
G
S
F
F
K
Q
A
K
K
Rat
Rattus norvegicus
Q3MHC2
600
67822
D309
F
K
H
I
K
A
F
D
R
T
F
A
D
N
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507374
782
88381
S452
G
E
G
S
R
K
G
S
F
F
K
Q
A
K
K
Chicken
Gallus gallus
Q5ZIH0
600
68170
D309
F
K
H
I
K
A
F
D
R
A
F
A
D
N
P
Frog
Xenopus laevis
Q9W799
783
88968
S452
N
E
G
S
R
K
G
S
F
F
K
Q
A
K
K
Zebra Danio
Brachydanio rerio
NP_001002384
790
89603
G453
G
E
G
G
R
K
G
G
F
F
K
Q
A
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3D6
756
85400
G448
P
E
G
R
H
H
S
G
F
F
K
S
N
K
R
Honey Bee
Apis mellifera
XP_394940
737
83538
G444
V
K
Q
E
S
K
P
G
F
F
K
Q
S
K
K
Nematode Worm
Caenorhab. elegans
O17403
843
95598
S480
W
D
N
Q
Q
K
A
S
F
F
K
T
T
K
K
Sea Urchin
Strong. purpuratus
XP_780045
776
88380
S453
D
T
G
K
K
G
T
S
F
F
K
T
V
K
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LKF9
739
82121
G445
H
D
V
I
G
S
H
G
P
A
Y
K
D
I
L
Baker's Yeast
Sacchar. cerevisiae
Q06224
779
87655
N461
D
N
E
V
H
V
F
N
P
R
N
C
V
E
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.4
99.8
99.6
N.A.
97.9
23.6
N.A.
98.4
23.6
91.3
86
N.A.
56
59.5
42.4
61.1
Protein Similarity:
100
93.4
100
99.8
N.A.
99.6
39.7
N.A.
99.4
40
96.8
93.1
N.A.
72.1
76.5
63.9
77.2
P-Site Identity:
100
0
100
100
N.A.
100
0
N.A.
100
0
93.3
86.6
N.A.
40
46.6
46.6
46.6
P-Site Similarity:
100
13.3
100
100
N.A.
100
13.3
N.A.
100
13.3
93.3
86.6
N.A.
46.6
60
60
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.4
20
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
57.4
41.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
0
13
7
0
0
13
0
13
44
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% C
% Asp:
13
13
0
0
0
0
0
13
7
0
0
0
19
0
0
% D
% Glu:
0
50
7
7
0
0
0
0
0
0
0
0
0
7
7
% E
% Phe:
13
0
0
0
0
0
19
0
69
69
13
0
0
0
0
% F
% Gly:
38
0
57
7
7
7
44
25
0
0
0
0
0
7
0
% G
% His:
7
0
13
7
13
7
7
7
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
19
0
0
0
0
0
0
0
0
0
7
0
% I
% Lys:
0
19
0
7
25
57
7
0
0
0
69
7
7
69
63
% K
% Leu:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
7
7
0
0
0
% M
% Asn:
7
7
7
0
0
0
0
7
0
0
7
0
7
13
0
% N
% Pro:
13
0
0
0
0
0
7
0
13
0
0
0
0
0
13
% P
% Gln:
0
0
7
7
7
0
0
0
0
0
0
50
0
0
0
% Q
% Arg:
0
0
0
7
44
0
0
0
13
7
0
0
0
0
7
% R
% Ser:
0
7
0
38
7
7
7
50
0
0
0
7
7
0
0
% S
% Thr:
0
7
0
0
0
7
7
0
0
7
0
13
7
0
0
% T
% Val:
7
0
7
7
0
7
0
0
0
0
0
0
13
0
7
% V
% Trp:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _