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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CPSF2
All Species:
25.15
Human Site:
S419
Identified Species:
36.89
UniProt:
Q9P2I0
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P2I0
NP_059133.1
782
88487
S419
S
K
E
A
D
I
D
S
S
D
E
S
D
I
E
Chimpanzee
Pan troglodytes
XP_001147204
731
82848
A406
E
K
L
K
K
E
A
A
K
K
L
E
Q
S
K
Rhesus Macaque
Macaca mulatta
XP_001092942
782
88454
S419
S
K
E
A
D
I
D
S
S
D
E
S
D
I
E
Dog
Lupus familis
XP_537353
782
88470
S419
S
K
E
A
D
I
D
S
S
D
E
S
D
V
E
Cat
Felis silvestris
Mouse
Mus musculus
O35218
782
88364
S419
S
K
E
A
D
I
D
S
S
D
E
S
D
V
E
Rat
Rattus norvegicus
Q3MHC2
600
67822
N276
T
G
L
T
E
K
A
N
H
Y
Y
K
L
F
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507374
782
88381
S419
S
K
E
A
D
I
D
S
S
D
E
S
D
V
E
Chicken
Gallus gallus
Q5ZIH0
600
68170
N276
T
G
L
T
E
K
A
N
H
Y
Y
K
L
F
I
Frog
Xenopus laevis
Q9W799
783
88968
S419
S
K
E
A
D
L
D
S
S
D
D
S
D
V
E
Zebra Danio
Brachydanio rerio
NP_001002384
790
89603
S420
K
E
V
D
L
D
S
S
D
E
S
D
M
E
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3D6
756
85400
E415
L
I
V
K
P
D
V
E
E
E
S
S
S
E
S
Honey Bee
Apis mellifera
XP_394940
737
83538
M411
E
Q
L
K
Q
E
Q
M
E
T
A
D
V
S
S
Nematode Worm
Caenorhab. elegans
O17403
843
95598
P447
D
I
A
A
P
I
V
P
R
H
S
E
K
D
F
Sea Urchin
Strong. purpuratus
XP_780045
776
88380
S420
Q
R
L
E
G
D
S
S
D
E
S
E
E
E
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LKF9
739
82121
K412
A
L
R
A
S
L
V
K
E
E
E
T
K
A
S
Baker's Yeast
Sacchar. cerevisiae
Q06224
779
87655
L428
I
S
A
P
N
I
I
L
V
H
G
E
A
N
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.4
99.8
99.6
N.A.
97.9
23.6
N.A.
98.4
23.6
91.3
86
N.A.
56
59.5
42.4
61.1
Protein Similarity:
100
93.4
100
99.8
N.A.
99.6
39.7
N.A.
99.4
40
96.8
93.1
N.A.
72.1
76.5
63.9
77.2
P-Site Identity:
100
6.6
100
93.3
N.A.
93.3
0
N.A.
93.3
0
80
6.6
N.A.
6.6
0
13.3
6.6
P-Site Similarity:
100
20
100
100
N.A.
100
20
N.A.
100
20
100
26.6
N.A.
13.3
6.6
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.4
20
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
57.4
41.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
13
50
0
0
19
7
0
0
7
0
7
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
7
38
19
38
0
13
38
7
13
38
7
7
% D
% Glu:
13
7
38
7
13
13
0
7
19
25
38
25
7
19
38
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
7
% F
% Gly:
0
13
0
0
7
0
0
0
0
0
7
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
13
13
0
0
0
0
0
% H
% Ile:
7
13
0
0
0
44
7
0
0
0
0
0
0
13
13
% I
% Lys:
7
44
0
19
7
13
0
7
7
7
0
13
13
0
7
% K
% Leu:
7
7
32
0
7
13
0
7
0
0
7
0
13
0
0
% L
% Met:
0
0
0
0
0
0
0
7
0
0
0
0
7
0
7
% M
% Asn:
0
0
0
0
7
0
0
13
0
0
0
0
0
7
0
% N
% Pro:
0
0
0
7
13
0
0
7
0
0
0
0
0
0
7
% P
% Gln:
7
7
0
0
7
0
7
0
0
0
0
0
7
0
0
% Q
% Arg:
0
7
7
0
0
0
0
0
7
0
0
0
0
0
0
% R
% Ser:
38
7
0
0
7
0
13
50
38
0
25
44
7
13
19
% S
% Thr:
13
0
0
13
0
0
0
0
0
7
0
7
0
0
0
% T
% Val:
0
0
13
0
0
0
19
0
7
0
0
0
7
25
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
13
13
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _