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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP35
All Species:
7.88
Human Site:
S976
Identified Species:
14.44
UniProt:
Q9P2H5
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P2H5
NP_065849.1
1017
113348
S976
R
S
R
A
A
Y
I
S
A
L
P
T
S
P
H
Chimpanzee
Pan troglodytes
XP_517457
1042
116629
L1000
L
N
A
R
A
R
A
L
Q
A
A
S
A
S
C
Rhesus Macaque
Macaca mulatta
XP_001092815
1041
116552
L999
L
N
A
R
A
R
A
L
Q
A
A
S
A
S
C
Dog
Lupus familis
XP_542286
1072
119038
S1031
R
S
R
A
A
Y
I
S
A
L
P
A
S
P
H
Cat
Felis silvestris
Mouse
Mus musculus
Q8BW70
1042
116083
L1000
L
N
A
R
A
R
A
L
Q
A
A
S
A
S
C
Rat
Rattus norvegicus
XP_238899
1007
111999
S967
R
S
R
A
A
Y
I
S
T
L
P
A
P
P
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513216
898
98952
Q857
N
A
R
T
R
A
L
Q
A
A
S
A
S
C
S
Chicken
Gallus gallus
XP_417222
997
112612
D970
W
W
R
D
F
E
R
D
K
D
D
D
S
S
S
Frog
Xenopus laevis
NP_001087645
1037
116290
A994
E
L
N
A
R
T
R
A
L
Q
N
T
S
A
S
Zebra Danio
Brachydanio rerio
XP_001919108
1014
112064
A971
E
L
N
A
R
T
R
A
L
Q
A
T
S
A
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610784
852
94928
H811
F
K
R
G
N
S
G
H
G
N
A
F
V
S
R
Honey Bee
Apis mellifera
XP_395580
833
95824
I805
Q
R
G
R
H
N
S
I
L
F
R
K
N
E
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001178896
1119
124137
L1057
D
A
I
Q
K
D
N
L
H
Y
I
Q
E
R
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
38.2
38.7
86.4
N.A.
38.9
88.7
N.A.
34.1
64.6
37
38.6
N.A.
24.4
25.3
N.A.
34.1
Protein Similarity:
100
54.9
55.1
88.3
N.A.
55.7
92.4
N.A.
49.4
76.7
54.6
55.2
N.A.
41.8
44.6
N.A.
50.4
P-Site Identity:
100
6.6
6.6
93.3
N.A.
6.6
80
N.A.
20
13.3
20
20
N.A.
6.6
0
N.A.
0
P-Site Similarity:
100
26.6
26.6
93.3
N.A.
26.6
80
N.A.
33.3
13.3
26.6
26.6
N.A.
6.6
20
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
24
39
47
8
24
16
24
31
39
24
24
16
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
24
% C
% Asp:
8
0
0
8
0
8
0
8
0
8
8
8
0
0
0
% D
% Glu:
16
0
0
0
0
8
0
0
0
0
0
0
8
8
8
% E
% Phe:
8
0
0
0
8
0
0
0
0
8
0
8
0
0
0
% F
% Gly:
0
0
8
8
0
0
8
0
8
0
0
0
0
0
0
% G
% His:
0
0
0
0
8
0
0
8
8
0
0
0
0
0
24
% H
% Ile:
0
0
8
0
0
0
24
8
0
0
8
0
0
0
0
% I
% Lys:
0
8
0
0
8
0
0
0
8
0
0
8
0
0
0
% K
% Leu:
24
16
0
0
0
0
8
31
24
24
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
24
16
0
8
8
8
0
0
8
8
0
8
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
24
0
8
24
0
% P
% Gln:
8
0
0
8
0
0
0
8
24
16
0
8
0
0
0
% Q
% Arg:
24
8
47
31
24
24
24
0
0
0
8
0
0
8
8
% R
% Ser:
0
24
0
0
0
8
8
24
0
0
8
24
47
39
31
% S
% Thr:
0
0
0
8
0
16
0
0
8
0
0
24
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% V
% Trp:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
24
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _