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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SIPA1L2
All Species:
19.39
Human Site:
Y220
Identified Species:
71.11
UniProt:
Q9P2F8
Number Species:
6
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P2F8
NP_065859.3
1722
190438
Y220
R
G
Y
R
V
E
N
Y
D
H
K
A
M
V
P
Chimpanzee
Pan troglodytes
XP_001151957
1722
190494
Y220
R
G
Y
R
V
E
N
Y
D
H
K
A
M
V
P
Rhesus Macaque
Macaca mulatta
XP_001112448
1640
181456
Y220
R
G
Y
R
V
E
N
Y
D
H
K
A
M
V
P
Dog
Lupus familis
XP_546087
1720
190046
Y218
R
G
Y
R
V
E
N
Y
D
H
K
A
M
A
P
Cat
Felis silvestris
Mouse
Mus musculus
Q80TE4
1722
189352
Y221
R
G
Y
R
I
E
S
Y
D
P
K
V
T
G
S
Rat
Rattus norvegicus
Q5JCS6
1722
189634
Y221
R
G
Y
R
I
E
S
Y
D
P
K
V
T
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A5PF44
1015
114125
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
94.1
95
N.A.
91.1
90.8
N.A.
N.A.
N.A.
N.A.
22.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
94.7
97.5
N.A.
95.4
94.8
N.A.
N.A.
N.A.
N.A.
33.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
53.3
53.3
N.A.
N.A.
N.A.
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
66.6
66.6
N.A.
N.A.
N.A.
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
58
0
15
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
86
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
86
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
86
0
0
0
0
0
0
0
0
0
0
0
15
0
% G
% His:
0
0
0
0
0
0
0
0
0
58
0
0
0
0
0
% H
% Ile:
0
0
0
0
29
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
86
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
58
0
0
% M
% Asn:
0
0
0
0
0
0
58
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
29
0
0
0
0
58
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
86
0
0
86
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
29
0
0
0
0
0
0
15
29
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
29
0
0
% T
% Val:
0
0
0
0
58
0
0
0
0
0
0
29
0
43
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
86
0
0
0
0
86
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _