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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MST4 All Species: 10.91
Human Site: S411 Identified Species: 20
UniProt: Q9P289 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P289 NP_057626.2 416 46529 S411 I E K F Q K C S A D E S P _ _
Chimpanzee Pan troglodytes XP_521266 579 63278 S549 V Q N G A V F S R R I P L R N
Rhesus Macaque Macaca mulatta A4K2T0 487 55587 L474 Q S K R Q P I L D A I E A K K
Dog Lupus familis XP_549261 626 68824 S621 I E K F Q K C S A D E S P _ _
Cat Felis silvestris
Mouse Mus musculus Q99JT2 416 46595 S411 I E K F Q K C S A D E S P _ _
Rat Rattus norvegicus O54748 491 56103 L478 S A K R Q P I L D A M D A K K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514828 344 38700
Chicken Gallus gallus Q5ZJK4 486 55318 L473 Q S K R Q P I L D A I E A K K
Frog Xenopus laevis Q6IP06 493 56486 L480 N A K R Q P I L D A M D A K K
Zebra Danio Brachydanio rerio Q7ZUQ3 492 56062 L479 T A K R Q P I L D A M D A K K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8T0S6 669 75091 S569 N Q P N L L L S N A A P M G Q
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9NB31 497 55620 E491 Q P I L D V I E I K K R L Q _
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P38692 1080 117043 N992 I P S G T Q F N H I L S S A A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 60.4 39.2 66.2 N.A. 98 38.7 N.A. 73 38.4 38.1 37.4 N.A. 28.7 N.A. 34.8 N.A.
Protein Similarity: 100 62 56.8 66.4 N.A. 99.2 57 N.A. 78.8 56.3 55.9 55.6 N.A. 43.9 N.A. 53.7 N.A.
P-Site Identity: 100 6.6 13.3 100 N.A. 100 13.3 N.A. 0 13.3 13.3 13.3 N.A. 6.6 N.A. 0 N.A.
P-Site Similarity: 100 20 13.3 100 N.A. 100 13.3 N.A. 0 13.3 13.3 13.3 N.A. 20 N.A. 7.1 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.5 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 28.7 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 24 0 0 8 0 0 0 24 47 8 0 39 8 8 % A
% Cys: 0 0 0 0 0 0 24 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 8 0 0 0 39 24 0 24 0 0 0 % D
% Glu: 0 24 0 0 0 0 0 8 0 0 24 16 0 0 0 % E
% Phe: 0 0 0 24 0 0 16 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 16 0 0 0 0 0 0 0 0 0 8 0 % G
% His: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % H
% Ile: 31 0 8 0 0 0 47 0 8 8 24 0 0 0 0 % I
% Lys: 0 0 62 0 0 24 0 0 0 8 8 0 0 39 39 % K
% Leu: 0 0 0 8 8 8 8 39 0 0 8 0 16 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 24 0 8 0 0 % M
% Asn: 16 0 8 8 0 0 0 8 8 0 0 0 0 0 8 % N
% Pro: 0 16 8 0 0 39 0 0 0 0 0 16 24 0 0 % P
% Gln: 24 16 0 0 62 8 0 0 0 0 0 0 0 8 8 % Q
% Arg: 0 0 0 39 0 0 0 0 8 8 0 8 0 8 0 % R
% Ser: 8 16 8 0 0 0 0 39 0 0 0 31 8 0 0 % S
% Thr: 8 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % T
% Val: 8 0 0 0 0 16 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 24 31 % _