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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MST4 All Species: 15.15
Human Site: S315 Identified Species: 27.78
UniProt: Q9P289 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P289 NP_057626.2 416 46529 S315 G S D S E S T S R E N N T H P
Chimpanzee Pan troglodytes XP_521266 579 63278 F454 F T K S F K E F I D A C L N K
Rhesus Macaque Macaca mulatta A4K2T0 487 55587 E322 D D E E N S E E D E M D S G T
Dog Lupus familis XP_549261 626 68824 S525 G S D S E S T S R E N N T H P
Cat Felis silvestris
Mouse Mus musculus Q99JT2 416 46595 S315 G S D S E S S S R E S N P H P
Rat Rattus norvegicus O54748 491 56103 S331 H T M V K T S S E G V G T M R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514828 344 38700 P250 N K E N N S H P E W S F T T V
Chicken Gallus gallus Q5ZJK4 486 55318 E321 E D E E N S E E D E T D S G T
Frog Xenopus laevis Q6IP06 493 56486 S330 H T M V K T N S E S A G T M R
Zebra Danio Brachydanio rerio Q7ZUQ3 492 56062 E318 D D E N S E E E V E V D S H T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8T0S6 669 75091 L334 A A S Q A K S L A T Q E N G M
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9NB31 497 55620 S325 G N D A T L L S E G M S T M I
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P38692 1080 117043 S317 S I P E N E P S K P S E A P K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 60.4 39.2 66.2 N.A. 98 38.7 N.A. 73 38.4 38.1 37.4 N.A. 28.7 N.A. 34.8 N.A.
Protein Similarity: 100 62 56.8 66.4 N.A. 99.2 57 N.A. 78.8 56.3 55.9 55.6 N.A. 43.9 N.A. 53.7 N.A.
P-Site Identity: 100 6.6 13.3 100 N.A. 80 13.3 N.A. 13.3 13.3 13.3 13.3 N.A. 0 N.A. 26.6 N.A.
P-Site Similarity: 100 26.6 33.3 100 N.A. 93.3 40 N.A. 33.3 33.3 33.3 40 N.A. 13.3 N.A. 46.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.5 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 28.7 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 0 8 8 0 0 0 8 0 16 0 8 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % C
% Asp: 16 24 31 0 0 0 0 0 16 8 0 24 0 0 0 % D
% Glu: 8 0 31 24 24 16 31 24 31 47 0 16 0 0 0 % E
% Phe: 8 0 0 0 8 0 0 8 0 0 0 8 0 0 0 % F
% Gly: 31 0 0 0 0 0 0 0 0 16 0 16 0 24 0 % G
% His: 16 0 0 0 0 0 8 0 0 0 0 0 0 31 0 % H
% Ile: 0 8 0 0 0 0 0 0 8 0 0 0 0 0 8 % I
% Lys: 0 8 8 0 16 16 0 0 8 0 0 0 0 0 16 % K
% Leu: 0 0 0 0 0 8 8 8 0 0 0 0 8 0 0 % L
% Met: 0 0 16 0 0 0 0 0 0 0 16 0 0 24 8 % M
% Asn: 8 8 0 16 31 0 8 0 0 0 16 24 8 8 0 % N
% Pro: 0 0 8 0 0 0 8 8 0 8 0 0 8 8 24 % P
% Gln: 0 0 0 8 0 0 0 0 0 0 8 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 24 0 0 0 0 0 16 % R
% Ser: 8 24 8 31 8 47 24 54 0 8 24 8 24 0 0 % S
% Thr: 0 24 0 0 8 16 16 0 0 8 8 0 47 8 24 % T
% Val: 0 0 0 16 0 0 0 0 8 0 16 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _