Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MST4 All Species: 9.09
Human Site: S137 Identified Species: 16.67
UniProt: Q9P289 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P289 NP_057626.2 416 46529 S137 K G L D Y L H S E K K I H R D
Chimpanzee Pan troglodytes XP_521266 579 63278 D270 E A E D E I E D I Q Q E I T V
Rhesus Macaque Macaca mulatta A4K2T0 487 55587 F142 K G L E Y L H F M R K I H R D
Dog Lupus familis XP_549261 626 68824 S347 K G L D Y L H S E K K I H R D
Cat Felis silvestris
Mouse Mus musculus Q99JT2 416 46595 S137 K G L D Y L H S E K K I H R D
Rat Rattus norvegicus O54748 491 56103 F139 K G L E Y L H F M R K I H R D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514828 344 38700 V78 R D I K A A N V L L S E Q G D
Chicken Gallus gallus Q5ZJK4 486 55318 F141 K G L E Y L H F M R K I H R D
Frog Xenopus laevis Q6IP06 493 56486 F138 K G L E Y L H F M R K I H R D
Zebra Danio Brachydanio rerio Q7ZUQ3 492 56062 F138 K G L E Y L H F M R K I H R D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8T0S6 669 75091 L154 Q G L V Y L H L R R K I H R D
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9NB31 497 55620 D147 K G L Q Y L H D L K K I H R D
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P38692 1080 117043 K137 V A L K C I H K D N V I H R D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 60.4 39.2 66.2 N.A. 98 38.7 N.A. 73 38.4 38.1 37.4 N.A. 28.7 N.A. 34.8 N.A.
Protein Similarity: 100 62 56.8 66.4 N.A. 99.2 57 N.A. 78.8 56.3 55.9 55.6 N.A. 43.9 N.A. 53.7 N.A.
P-Site Identity: 100 6.6 73.3 100 N.A. 100 73.3 N.A. 6.6 73.3 73.3 73.3 N.A. 66.6 N.A. 80 N.A.
P-Site Similarity: 100 33.3 86.6 100 N.A. 100 86.6 N.A. 26.6 86.6 86.6 86.6 N.A. 80 N.A. 80 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.5 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 28.7 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 40 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 53.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 16 0 0 8 8 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 31 0 0 0 16 8 0 0 0 0 0 93 % D
% Glu: 8 0 8 39 8 0 8 0 24 0 0 16 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 39 0 0 0 0 0 0 0 % F
% Gly: 0 77 0 0 0 0 0 0 0 0 0 0 0 8 0 % G
% His: 0 0 0 0 0 0 85 0 0 0 0 0 85 0 0 % H
% Ile: 0 0 8 0 0 16 0 0 8 0 0 85 8 0 0 % I
% Lys: 70 0 0 16 0 0 0 8 0 31 77 0 0 0 0 % K
% Leu: 0 0 85 0 0 77 0 8 16 8 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 39 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 8 0 0 8 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 8 0 0 8 0 0 0 0 0 8 8 0 8 0 0 % Q
% Arg: 8 0 0 0 0 0 0 0 8 47 0 0 0 85 0 % R
% Ser: 0 0 0 0 0 0 0 24 0 0 8 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % T
% Val: 8 0 0 8 0 0 0 8 0 0 8 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 77 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _