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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP36
All Species:
6.67
Human Site:
T475
Identified Species:
13.33
UniProt:
Q9P275
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P275
NP_079366.3
1121
122652
T475
G
K
R
Q
D
S
G
T
M
K
K
P
H
T
T
Chimpanzee
Pan troglodytes
XP_001146571
1275
138595
M475
G
K
R
Q
D
S
G
M
M
K
K
P
H
I
T
Rhesus Macaque
Macaca mulatta
XP_001108648
1126
122953
T478
G
K
R
Q
D
S
G
T
M
K
K
L
H
S
T
Dog
Lupus familis
XP_540463
1117
122160
V475
K
R
L
D
P
V
T
V
K
K
L
P
A
T
E
Cat
Felis silvestris
Mouse
Mus musculus
B1AQJ2
1098
119895
M475
K
R
Q
D
S
V
M
M
R
K
L
P
A
P
E
Rat
Rattus norvegicus
NP_001100539
1005
109039
L401
W
Y
Q
M
N
D
S
L
V
H
S
S
N
V
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520693
1068
115594
N461
H
V
K
K
I
I
S
N
G
A
L
S
S
P
L
Chicken
Gallus gallus
XP_424101
643
69042
D39
S
V
C
K
S
V
S
D
T
Y
D
P
Y
L
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_688241
1104
122640
Q475
P
A
Q
L
R
K
I
Q
S
V
D
G
G
L
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VRP5
1085
118669
S445
G
H
Y
T
A
I
G
S
T
D
T
G
S
F
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795476
1126
125182
T489
P
I
A
R
P
K
P
T
P
P
R
P
T
T
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FPS4
859
94885
L255
S
N
K
F
D
P
F
L
D
L
S
L
D
I
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78.5
92
74.6
N.A.
71.8
67.4
N.A.
62.1
37.8
N.A.
47.6
N.A.
24.5
N.A.
N.A.
27.8
Protein Similarity:
100
81.4
94.4
83.1
N.A.
80.4
75.3
N.A.
70.6
45.2
N.A.
61.7
N.A.
43.2
N.A.
N.A.
44.2
P-Site Identity:
100
86.6
86.6
20
N.A.
13.3
0
N.A.
0
6.6
N.A.
0
N.A.
13.3
N.A.
N.A.
20
P-Site Similarity:
100
86.6
93.3
26.6
N.A.
26.6
26.6
N.A.
13.3
20
N.A.
6.6
N.A.
20
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
9
0
9
0
0
0
0
9
0
0
17
0
0
% A
% Cys:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
17
34
9
0
9
9
9
17
0
9
0
9
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
17
% E
% Phe:
0
0
0
9
0
0
9
0
0
0
0
0
0
9
0
% F
% Gly:
34
0
0
0
0
0
34
0
9
0
0
17
9
0
9
% G
% His:
9
9
0
0
0
0
0
0
0
9
0
0
25
0
0
% H
% Ile:
0
9
0
0
9
17
9
0
0
0
0
0
0
17
0
% I
% Lys:
17
25
17
17
0
17
0
0
9
42
25
0
0
0
9
% K
% Leu:
0
0
9
9
0
0
0
17
0
9
25
17
0
17
9
% L
% Met:
0
0
0
9
0
0
9
17
25
0
0
0
0
0
0
% M
% Asn:
0
9
0
0
9
0
0
9
0
0
0
0
9
0
0
% N
% Pro:
17
0
0
0
17
9
9
0
9
9
0
50
0
17
9
% P
% Gln:
0
0
25
25
0
0
0
9
0
0
0
0
0
0
0
% Q
% Arg:
0
17
25
9
9
0
0
0
9
0
9
0
0
0
0
% R
% Ser:
17
0
0
0
17
25
25
9
9
0
17
17
17
9
9
% S
% Thr:
0
0
0
9
0
0
9
25
17
0
9
0
9
25
25
% T
% Val:
0
17
0
0
0
25
0
9
9
9
0
0
0
9
0
% V
% Trp:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
9
0
0
0
0
0
0
9
0
0
9
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _