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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: USP36 All Species: 14.24
Human Site: S749 Identified Species: 28.48
UniProt: Q9P275 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P275 NP_079366.3 1121 122652 S749 S P A P Q S S S R L Q P P F S
Chimpanzee Pan troglodytes XP_001146571 1275 138595 S749 S P A P Q S S S R L Q P P F S
Rhesus Macaque Macaca mulatta XP_001108648 1126 122953 S752 S P A P Q S S S R L Q P P F S
Dog Lupus familis XP_540463 1117 122160 H750 P A P R P S S H L K L P V G P
Cat Felis silvestris
Mouse Mus musculus B1AQJ2 1098 119895 T745 A P A P R P S T H P H S A S L
Rat Rattus norvegicus NP_001100539 1005 109039 E671 A L S S T T T E P T S L M S P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520693 1068 115594 A731 K T T H L V F A S P W P V S K
Chicken Gallus gallus XP_424101 643 69042 S309 R R P K K P P S P Q R P P A P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_688241 1104 122640 S745 S T T P L L A S P V V K N K K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VRP5 1085 118669 A718 G S H T N G S A S S S V H V N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795476 1126 125182 K761 R K T D S P L K L T I T T N G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FPS4 859 94885 K525 A P T V L V Q K D L N T K E I
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 78.5 92 74.6 N.A. 71.8 67.4 N.A. 62.1 37.8 N.A. 47.6 N.A. 24.5 N.A. N.A. 27.8
Protein Similarity: 100 81.4 94.4 83.1 N.A. 80.4 75.3 N.A. 70.6 45.2 N.A. 61.7 N.A. 43.2 N.A. N.A. 44.2
P-Site Identity: 100 100 100 20 N.A. 26.6 0 N.A. 6.6 20 N.A. 20 N.A. 6.6 N.A. N.A. 0
P-Site Similarity: 100 100 100 20 N.A. 46.6 26.6 N.A. 13.3 33.3 N.A. 33.3 N.A. 20 N.A. N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. 25.6 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 41.2 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 25 9 34 0 0 0 9 17 0 0 0 0 9 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 9 0 0 0 0 9 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 9 0 0 0 0 0 9 0 % E
% Phe: 0 0 0 0 0 0 9 0 0 0 0 0 0 25 0 % F
% Gly: 9 0 0 0 0 9 0 0 0 0 0 0 0 9 9 % G
% His: 0 0 9 9 0 0 0 9 9 0 9 0 9 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 9 % I
% Lys: 9 9 0 9 9 0 0 17 0 9 0 9 9 9 17 % K
% Leu: 0 9 0 0 25 9 9 0 17 34 9 9 0 0 9 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % M
% Asn: 0 0 0 0 9 0 0 0 0 0 9 0 9 9 9 % N
% Pro: 9 42 17 42 9 25 9 0 25 17 0 50 34 0 25 % P
% Gln: 0 0 0 0 25 0 9 0 0 9 25 0 0 0 0 % Q
% Arg: 17 9 0 9 9 0 0 0 25 0 9 0 0 0 0 % R
% Ser: 34 9 9 9 9 34 50 42 17 9 17 9 0 25 25 % S
% Thr: 0 17 34 9 9 9 9 9 0 17 0 17 9 0 0 % T
% Val: 0 0 0 9 0 17 0 0 0 9 9 9 17 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _