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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIAA1468 All Species: 23.33
Human Site: S503 Identified Species: 42.78
UniProt: Q9P260 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P260 NP_065905.2 1216 134630 S503 F C R M S A D S R L G Y E V S
Chimpanzee Pan troglodytes XP_001144840 1216 134598 S503 F C R M S A D S R L G Y E V S
Rhesus Macaque Macaca mulatta XP_001089393 1216 134711 S503 F C R M S A D S R L G Y E V S
Dog Lupus familis XP_857532 1213 134286 R501 C R M S A D S R L G S E V S R
Cat Felis silvestris
Mouse Mus musculus Q148V7 1216 134568 S503 F C R M S A D S R L G S E V S
Rat Rattus norvegicus NP_001128018 1218 134632 S505 F C R M S A D S R L G S E V S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520447 566 63684
Chicken Gallus gallus XP_418993 1101 123185 G469 Q R Q M I L T G C V A F A R H
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q6P6Y1 1189 132113 S476 F C R M S A D S R L G S E V S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_624982 1101 123579 F467 R Q L I L A G F I A M A K L E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001188840 523 57914
Poplar Tree Populus trichocarpa XP_002305839 1140 127435 T472 E C H P D S G T R D S L T H T
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_197125 1180 132290 H470 V P Y V L I N H R E E L L P L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 97.4 95.6 N.A. 93.3 92.6 N.A. 44.1 80 N.A. 74.5 N.A. N.A. 32.3 N.A. 23.5
Protein Similarity: 100 99.9 98.2 97.3 N.A. 95.9 95.5 N.A. 45.1 84.2 N.A. 83.3 N.A. N.A. 50.6 N.A. 31.9
P-Site Identity: 100 100 100 0 N.A. 93.3 93.3 N.A. 0 6.6 N.A. 93.3 N.A. N.A. 6.6 N.A. 0
P-Site Similarity: 100 100 100 6.6 N.A. 93.3 93.3 N.A. 0 26.6 N.A. 93.3 N.A. N.A. 26.6 N.A. 0
Percent
Protein Identity: 23.3 N.A. N.A. 23.3 N.A. N.A.
Protein Similarity: 41.2 N.A. N.A. 41.6 N.A. N.A.
P-Site Identity: 13.3 N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: 33.3 N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 8 54 0 0 0 8 8 8 8 0 0 % A
% Cys: 8 54 0 0 0 0 0 0 8 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 8 8 47 0 0 8 0 0 0 0 0 % D
% Glu: 8 0 0 0 0 0 0 0 0 8 8 8 47 0 8 % E
% Phe: 47 0 0 0 0 0 0 8 0 0 0 8 0 0 0 % F
% Gly: 0 0 0 0 0 0 16 8 0 8 47 0 0 0 0 % G
% His: 0 0 8 0 0 0 0 8 0 0 0 0 0 8 8 % H
% Ile: 0 0 0 8 8 8 0 0 8 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % K
% Leu: 0 0 8 0 16 8 0 0 8 47 0 16 8 8 8 % L
% Met: 0 0 8 54 0 0 0 0 0 0 8 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % N
% Pro: 0 8 0 8 0 0 0 0 0 0 0 0 0 8 0 % P
% Gln: 8 8 8 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 8 16 47 0 0 0 0 8 62 0 0 0 0 8 8 % R
% Ser: 0 0 0 8 47 8 8 47 0 0 16 24 0 8 47 % S
% Thr: 0 0 0 0 0 0 8 8 0 0 0 0 8 0 8 % T
% Val: 8 0 0 8 0 0 0 0 0 8 0 0 8 47 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 0 0 0 0 0 0 0 0 24 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _