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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS18
All Species:
40
Human Site:
Y671
Identified Species:
67.69
UniProt:
Q9P253
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P253
NP_065908.1
973
110186
Y671
H
N
Y
L
L
S
L
Y
A
R
G
R
P
D
S
Chimpanzee
Pan troglodytes
XP_523187
973
110161
Y671
H
N
Y
L
L
S
L
Y
A
R
G
R
P
D
S
Rhesus Macaque
Macaca mulatta
XP_001099146
973
110096
Y671
H
N
Y
L
L
S
L
Y
A
R
G
R
P
D
S
Dog
Lupus familis
XP_544627
1095
122945
Y793
H
N
Y
L
L
S
L
Y
A
R
G
Q
P
A
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8R307
973
110200
Y671
H
N
Y
L
L
S
L
Y
A
R
G
Q
P
A
S
Rat
Rattus norvegicus
NP_001099969
973
110167
Y671
H
N
Y
L
L
S
L
Y
A
R
G
Q
P
A
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506026
612
69591
W370
P
R
Q
L
V
D
A
W
I
A
Q
G
P
R
L
Chicken
Gallus gallus
XP_421131
974
112556
Y671
H
N
Y
L
L
S
L
Y
A
L
C
R
P
D
S
Frog
Xenopus laevis
NP_001085645
968
111576
Y665
H
N
Y
L
L
S
L
Y
A
Q
F
R
S
D
S
Zebra Danio
Brachydanio rerio
P59015
974
113248
Y671
H
N
Y
L
L
S
L
Y
A
K
H
K
P
D
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24314
1002
115316
Y704
H
N
F
L
L
H
L
Y
A
E
H
E
P
K
L
Honey Bee
Apis mellifera
XP_396968
718
83450
T476
S
A
L
L
G
L
W
T
T
A
V
D
L
A
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_172709
994
113061
Y649
H
S
L
L
L
S
L
Y
A
K
Q
E
D
D
G
Baker's Yeast
Sacchar. cerevisiae
P27801
918
107380
D639
I
L
Y
M
M
I
T
D
P
R
N
D
M
I
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99.6
86.6
N.A.
95.7
95.1
N.A.
52.8
74
68.3
65.9
N.A.
34.7
34.6
N.A.
N.A.
Protein Similarity:
100
99.9
99.9
87.4
N.A.
97.5
97.1
N.A.
56.4
86.4
83.2
82.4
N.A.
53.6
51.4
N.A.
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
86.6
86.6
N.A.
13.3
86.6
80
73.3
N.A.
53.3
6.6
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
26.6
86.6
86.6
93.3
N.A.
60
6.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
32.7
21.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.3
41.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
53.3
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
8
0
79
15
0
0
0
29
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
0
8
0
0
0
15
8
50
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
8
0
15
0
0
0
% E
% Phe:
0
0
8
0
0
0
0
0
0
0
8
0
0
0
0
% F
% Gly:
0
0
0
0
8
0
0
0
0
0
43
8
0
0
8
% G
% His:
79
0
0
0
0
8
0
0
0
0
15
0
0
0
0
% H
% Ile:
8
0
0
0
0
8
0
0
8
0
0
0
0
8
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
15
0
8
0
8
0
% K
% Leu:
0
8
15
93
79
8
79
0
0
8
0
0
8
0
29
% L
% Met:
0
0
0
8
8
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
72
0
0
0
0
0
0
0
0
8
0
0
0
0
% N
% Pro:
8
0
0
0
0
0
0
0
8
0
0
0
72
0
0
% P
% Gln:
0
0
8
0
0
0
0
0
0
8
15
22
0
0
0
% Q
% Arg:
0
8
0
0
0
0
0
0
0
50
0
36
0
8
0
% R
% Ser:
8
8
0
0
0
72
0
0
0
0
0
0
8
0
58
% S
% Thr:
0
0
0
0
0
0
8
8
8
0
0
0
0
0
0
% T
% Val:
0
0
0
0
8
0
0
0
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
72
0
0
0
0
79
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _