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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS18
All Species:
26.97
Human Site:
Y516
Identified Species:
45.64
UniProt:
Q9P253
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P253
NP_065908.1
973
110186
Y516
D
P
E
A
L
T
L
Y
R
E
T
K
E
C
F
Chimpanzee
Pan troglodytes
XP_523187
973
110161
Y516
N
P
E
A
L
T
L
Y
R
E
T
K
E
C
F
Rhesus Macaque
Macaca mulatta
XP_001099146
973
110096
Y516
D
P
E
A
L
T
L
Y
R
E
T
K
E
C
F
Dog
Lupus familis
XP_544627
1095
122945
Y638
D
P
E
A
L
N
L
Y
R
E
T
R
E
R
F
Cat
Felis silvestris
Mouse
Mus musculus
Q8R307
973
110200
Y516
D
P
D
A
L
T
L
Y
R
D
T
R
E
C
F
Rat
Rattus norvegicus
NP_001099969
973
110167
Y516
D
P
D
A
L
N
L
Y
R
D
T
R
E
C
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506026
612
69591
E222
K
F
L
G
A
R
Q
E
A
A
L
A
E
F
L
Chicken
Gallus gallus
XP_421131
974
112556
Y516
D
P
S
Q
R
N
L
Y
L
D
T
R
E
K
F
Frog
Xenopus laevis
NP_001085645
968
111576
Y511
D
A
S
K
R
S
L
Y
L
K
A
R
D
D
F
Zebra Danio
Brachydanio rerio
P59015
974
113248
F516
D
E
G
K
Q
H
L
F
L
E
T
R
E
E
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24314
1002
115316
R552
P
D
K
D
E
E
W
R
S
S
W
Q
T
E
Y
Honey Bee
Apis mellifera
XP_396968
718
83450
L328
E
E
V
I
R
Q
H
L
Y
K
N
N
Y
L
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_172709
994
113061
N492
E
D
D
T
A
I
E
N
R
D
S
E
Y
H
S
Baker's Yeast
Sacchar. cerevisiae
P27801
918
107380
W471
D
E
D
N
L
L
N
W
N
L
N
L
K
E
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99.6
86.6
N.A.
95.7
95.1
N.A.
52.8
74
68.3
65.9
N.A.
34.7
34.6
N.A.
N.A.
Protein Similarity:
100
99.9
99.9
87.4
N.A.
97.5
97.1
N.A.
56.4
86.4
83.2
82.4
N.A.
53.6
51.4
N.A.
N.A.
P-Site Identity:
100
93.3
100
80
N.A.
80
73.3
N.A.
6.6
46.6
26.6
40
N.A.
0
0
N.A.
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
100
93.3
N.A.
6.6
60
53.3
53.3
N.A.
20
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
32.7
21.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.3
41.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
43
15
0
0
0
8
8
8
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
36
0
% C
% Asp:
65
15
29
8
0
0
0
0
0
29
0
0
8
8
0
% D
% Glu:
15
22
29
0
8
8
8
8
0
36
0
8
65
22
8
% E
% Phe:
0
8
0
0
0
0
0
8
0
0
0
0
0
8
65
% F
% Gly:
0
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
8
8
0
0
0
0
0
0
8
0
% H
% Ile:
0
0
0
8
0
8
0
0
0
0
0
0
0
0
0
% I
% Lys:
8
0
8
15
0
0
0
0
0
15
0
22
8
8
8
% K
% Leu:
0
0
8
0
50
8
65
8
22
8
8
8
0
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
8
0
22
8
8
8
0
15
8
0
0
0
% N
% Pro:
8
50
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
8
8
8
8
0
0
0
0
8
0
0
0
% Q
% Arg:
0
0
0
0
22
8
0
8
50
0
0
43
0
8
0
% R
% Ser:
0
0
15
0
0
8
0
0
8
8
8
0
0
0
8
% S
% Thr:
0
0
0
8
0
29
0
0
0
0
58
0
8
0
0
% T
% Val:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
8
8
0
0
8
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
58
8
0
0
0
15
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _