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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS18
All Species:
42.12
Human Site:
Y402
Identified Species:
71.28
UniProt:
Q9P253
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P253
NP_065908.1
973
110186
Y402
A
R
D
V
W
R
T
Y
L
D
M
N
R
F
D
Chimpanzee
Pan troglodytes
XP_523187
973
110161
Y402
A
R
D
V
W
R
T
Y
L
D
M
N
R
F
D
Rhesus Macaque
Macaca mulatta
XP_001099146
973
110096
Y402
A
R
D
V
W
R
T
Y
L
D
M
N
R
F
D
Dog
Lupus familis
XP_544627
1095
122945
Y524
A
R
D
V
W
R
T
Y
L
D
M
N
R
F
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8R307
973
110200
Y402
A
R
D
V
W
R
T
Y
L
D
M
N
R
F
D
Rat
Rattus norvegicus
NP_001099969
973
110167
Y402
A
R
D
V
W
R
T
Y
L
D
M
N
R
F
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506026
612
69591
G120
D
H
F
L
D
K
F
G
P
L
R
G
M
A
K
Chicken
Gallus gallus
XP_421131
974
112556
Y402
S
R
D
V
W
K
M
Y
M
N
M
N
K
F
D
Frog
Xenopus laevis
NP_001085645
968
111576
Y397
P
R
D
V
W
K
M
Y
M
S
M
G
K
F
D
Zebra Danio
Brachydanio rerio
P59015
974
113248
Y402
A
R
D
V
W
Q
M
Y
M
N
M
N
K
F
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24314
1002
115316
Y431
E
R
N
V
W
R
I
Y
L
D
K
G
Q
Y
E
Honey Bee
Apis mellifera
XP_396968
718
83450
K226
A
L
K
T
F
L
K
K
K
L
E
G
L
K
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_172709
994
113061
Y377
G
R
D
M
W
K
V
Y
L
D
L
K
V
Y
A
Baker's Yeast
Sacchar. cerevisiae
P27801
918
107380
S368
L
T
V
R
E
I
E
S
V
K
L
S
K
A
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99.6
86.6
N.A.
95.7
95.1
N.A.
52.8
74
68.3
65.9
N.A.
34.7
34.6
N.A.
N.A.
Protein Similarity:
100
99.9
99.9
87.4
N.A.
97.5
97.1
N.A.
56.4
86.4
83.2
82.4
N.A.
53.6
51.4
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
0
60
53.3
66.6
N.A.
46.6
6.6
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
13.3
93.3
73.3
93.3
N.A.
73.3
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
32.7
21.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.3
41.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
58
0
0
0
0
0
0
0
0
0
0
0
0
15
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
72
0
8
0
0
0
0
58
0
0
0
0
65
% D
% Glu:
8
0
0
0
8
0
8
0
0
0
8
0
0
0
8
% E
% Phe:
0
0
8
0
8
0
8
0
0
0
0
0
0
65
0
% F
% Gly:
8
0
0
0
0
0
0
8
0
0
0
29
0
0
0
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
8
8
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
8
0
0
29
8
8
8
8
8
8
29
8
8
% K
% Leu:
8
8
0
8
0
8
0
0
58
15
15
0
8
0
0
% L
% Met:
0
0
0
8
0
0
22
0
22
0
65
0
8
0
8
% M
% Asn:
0
0
8
0
0
0
0
0
0
15
0
58
0
0
0
% N
% Pro:
8
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
8
0
0
0
0
0
0
8
0
0
% Q
% Arg:
0
79
0
8
0
50
0
0
0
0
8
0
43
0
0
% R
% Ser:
8
0
0
0
0
0
0
8
0
8
0
8
0
0
0
% S
% Thr:
0
8
0
8
0
0
43
0
0
0
0
0
0
0
8
% T
% Val:
0
0
8
72
0
0
8
0
8
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
79
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
79
0
0
0
0
0
15
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _