KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS18
All Species:
31.21
Human Site:
Y314
Identified Species:
52.82
UniProt:
Q9P253
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P253
NP_065908.1
973
110186
Y314
S
E
E
R
V
W
E
Y
P
E
G
V
G
P
G
Chimpanzee
Pan troglodytes
XP_523187
973
110161
Y314
S
E
E
R
V
W
E
Y
P
E
G
V
G
P
G
Rhesus Macaque
Macaca mulatta
XP_001099146
973
110096
Y314
S
E
E
R
V
W
E
Y
P
E
G
V
G
P
G
Dog
Lupus familis
XP_544627
1095
122945
Y436
S
E
E
R
V
W
E
Y
P
E
G
V
G
P
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8R307
973
110200
Y314
S
E
E
R
V
W
E
Y
P
A
G
V
G
P
G
Rat
Rattus norvegicus
NP_001099969
973
110167
Y314
S
E
E
K
V
W
E
Y
P
A
G
I
G
P
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506026
612
69591
V41
R
R
E
K
D
P
E
V
A
Q
G
A
V
R
V
Chicken
Gallus gallus
XP_421131
974
112556
Y314
S
D
E
R
V
W
V
Y
P
S
D
I
D
I
T
Frog
Xenopus laevis
NP_001085645
968
111576
Y313
T
D
V
Q
V
W
E
Y
P
S
S
A
E
K
P
Zebra Danio
Brachydanio rerio
P59015
974
113248
Y314
S
D
V
Q
V
W
E
Y
T
Q
D
I
D
L
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24314
1002
115316
N334
L
I
G
N
T
L
I
N
L
D
F
E
K
T
M
Honey Bee
Apis mellifera
XP_396968
718
83450
N148
K
V
N
K
E
D
R
N
V
W
Q
V
Y
V
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_172709
994
113061
S285
N
K
A
L
L
D
Y
S
K
L
S
D
G
T
E
Baker's Yeast
Sacchar. cerevisiae
P27801
918
107380
D287
M
V
S
Q
L
N
N
D
V
V
F
H
E
T
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99.6
86.6
N.A.
95.7
95.1
N.A.
52.8
74
68.3
65.9
N.A.
34.7
34.6
N.A.
N.A.
Protein Similarity:
100
99.9
99.9
87.4
N.A.
97.5
97.1
N.A.
56.4
86.4
83.2
82.4
N.A.
53.6
51.4
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
80
N.A.
20
46.6
33.3
33.3
N.A.
0
6.6
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
33.3
60
53.3
60
N.A.
6.6
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
32.7
21.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.3
41.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
0
8
15
0
15
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
22
0
0
8
15
0
8
0
8
15
8
15
0
8
% D
% Glu:
0
43
58
0
8
0
65
0
0
29
0
8
15
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
15
0
0
0
0
% F
% Gly:
0
0
8
0
0
0
0
0
0
0
50
0
50
0
43
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
8
0
0
0
0
8
0
0
0
0
22
0
8
8
% I
% Lys:
8
8
0
22
0
0
0
0
8
0
0
0
8
8
0
% K
% Leu:
8
0
0
8
15
8
0
0
8
8
0
0
0
8
0
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
8
0
8
8
0
8
8
15
0
0
0
0
0
0
8
% N
% Pro:
0
0
0
0
0
8
0
0
58
0
0
0
0
43
8
% P
% Gln:
0
0
0
22
0
0
0
0
0
15
8
0
0
0
0
% Q
% Arg:
8
8
0
43
0
0
8
0
0
0
0
0
0
8
0
% R
% Ser:
58
0
8
0
0
0
0
8
0
15
15
0
0
0
0
% S
% Thr:
8
0
0
0
8
0
0
0
8
0
0
0
0
22
8
% T
% Val:
0
15
15
0
65
0
8
8
15
8
0
43
8
8
8
% V
% Trp:
0
0
0
0
0
65
0
0
0
8
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
65
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _