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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS18
All Species:
26.36
Human Site:
Y194
Identified Species:
44.62
UniProt:
Q9P253
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P253
NP_065908.1
973
110186
Y194
D
L
Y
F
R
P
L
Y
V
L
N
E
E
G
G
Chimpanzee
Pan troglodytes
XP_523187
973
110161
Y194
D
L
Y
F
R
P
L
Y
V
L
N
E
E
G
G
Rhesus Macaque
Macaca mulatta
XP_001099146
973
110096
Y194
D
L
Y
F
R
P
L
Y
V
L
N
E
E
G
G
Dog
Lupus familis
XP_544627
1095
122945
Y316
D
L
Y
F
R
P
L
Y
V
L
N
E
E
G
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8R307
973
110200
Y194
D
L
Y
F
R
P
L
Y
V
L
N
E
E
G
G
Rat
Rattus norvegicus
NP_001099969
973
110167
Y194
D
L
Y
F
R
P
L
Y
V
L
N
E
E
G
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506026
612
69591
Chicken
Gallus gallus
XP_421131
974
112556
Y194
D
Q
Y
F
R
L
V
Y
T
L
E
E
E
S
G
Frog
Xenopus laevis
NP_001085645
968
111576
H193
D
Q
Y
F
R
N
I
H
T
L
E
E
E
T
G
Zebra Danio
Brachydanio rerio
P59015
974
113248
H194
D
Q
Y
F
R
Q
V
H
Y
L
E
E
D
G
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24314
1002
115316
R219
L
Y
D
L
G
L
G
R
P
K
Y
P
I
T
G
Honey Bee
Apis mellifera
XP_396968
718
83450
T34
S
F
G
W
L
T
E
T
G
I
L
Y
A
Q
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_172709
994
113061
A170
E
L
P
E
A
F
K
A
L
Q
M
E
T
A
N
Baker's Yeast
Sacchar. cerevisiae
P27801
918
107380
D172
D
N
I
L
Y
W
R
D
V
T
N
M
K
F
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99.6
86.6
N.A.
95.7
95.1
N.A.
52.8
74
68.3
65.9
N.A.
34.7
34.6
N.A.
N.A.
Protein Similarity:
100
99.9
99.9
87.4
N.A.
97.5
97.1
N.A.
56.4
86.4
83.2
82.4
N.A.
53.6
51.4
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
0
60
53.3
46.6
N.A.
6.6
0
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
0
66.6
66.6
66.6
N.A.
6.6
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
32.7
21.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.3
41.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
8
0
0
0
0
8
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
72
0
8
0
0
0
0
8
0
0
0
0
8
0
0
% D
% Glu:
8
0
0
8
0
0
8
0
0
0
22
72
58
0
0
% E
% Phe:
0
8
0
65
0
8
0
0
0
0
0
0
0
8
0
% F
% Gly:
0
0
8
0
8
0
8
0
8
0
0
0
0
50
65
% G
% His:
0
0
0
0
0
0
0
15
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
8
0
0
8
0
0
8
0
8
% I
% Lys:
0
0
0
0
0
0
8
0
0
8
0
0
8
0
8
% K
% Leu:
8
50
0
15
8
15
43
0
8
65
8
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
8
0
0
0
% M
% Asn:
0
8
0
0
0
8
0
0
0
0
50
0
0
0
8
% N
% Pro:
0
0
8
0
0
43
0
0
8
0
0
8
0
0
8
% P
% Gln:
0
22
0
0
0
8
0
0
0
8
0
0
0
8
0
% Q
% Arg:
0
0
0
0
65
0
8
8
0
0
0
0
0
0
0
% R
% Ser:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% S
% Thr:
0
0
0
0
0
8
0
8
15
8
0
0
8
15
0
% T
% Val:
0
0
0
0
0
0
15
0
50
0
0
0
0
0
0
% V
% Trp:
0
0
0
8
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
65
0
8
0
0
50
8
0
8
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _