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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS18
All Species:
38.79
Human Site:
T449
Identified Species:
65.64
UniProt:
Q9P253
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P253
NP_065908.1
973
110186
T449
S
A
R
C
Y
A
L
T
Q
S
Y
F
E
E
I
Chimpanzee
Pan troglodytes
XP_523187
973
110161
T449
S
A
R
C
Y
A
L
T
Q
S
Y
F
E
E
I
Rhesus Macaque
Macaca mulatta
XP_001099146
973
110096
T449
S
A
R
C
Y
A
L
T
Q
S
Y
F
E
E
I
Dog
Lupus familis
XP_544627
1095
122945
T571
S
A
R
C
Y
A
L
T
Q
S
Y
F
E
E
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8R307
973
110200
T449
S
A
R
C
Y
A
L
T
Q
S
Y
F
E
E
I
Rat
Rattus norvegicus
NP_001099969
973
110167
T449
S
A
R
C
Y
A
L
T
Q
S
Y
F
E
E
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506026
612
69591
A167
D
M
N
R
F
D
L
A
K
E
Y
C
R
E
R
Chicken
Gallus gallus
XP_421131
974
112556
T449
S
A
K
C
Y
A
L
T
Q
N
Y
F
E
E
I
Frog
Xenopus laevis
NP_001085645
968
111576
T444
S
A
K
C
Y
A
L
T
Q
K
Y
F
E
E
V
Zebra Danio
Brachydanio rerio
P59015
974
113248
T449
S
A
K
C
Y
A
L
T
Q
N
Y
F
E
E
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24314
1002
115316
T478
A
A
D
Y
Y
A
E
T
D
K
S
F
E
E
V
Honey Bee
Apis mellifera
XP_396968
718
83450
L273
H
D
S
Q
Y
L
E
L
Q
K
Q
F
D
S
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_172709
994
113061
N424
A
S
F
Y
A
K
I
N
Y
V
I
S
F
E
E
Baker's Yeast
Sacchar. cerevisiae
P27801
918
107380
D415
L
Q
I
K
D
Y
N
D
L
N
V
I
L
I
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99.6
86.6
N.A.
95.7
95.1
N.A.
52.8
74
68.3
65.9
N.A.
34.7
34.6
N.A.
N.A.
Protein Similarity:
100
99.9
99.9
87.4
N.A.
97.5
97.1
N.A.
56.4
86.4
83.2
82.4
N.A.
53.6
51.4
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
20
86.6
80
86.6
N.A.
46.6
20
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
33.3
100
93.3
100
N.A.
60
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
32.7
21.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.3
41.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
72
0
0
8
72
0
8
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
65
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
8
8
8
0
8
8
0
8
8
0
0
0
8
0
0
% D
% Glu:
0
0
0
0
0
0
15
0
0
8
0
0
72
86
8
% E
% Phe:
0
0
8
0
8
0
0
0
0
0
0
79
8
0
8
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
8
0
0
0
8
8
0
8
58
% I
% Lys:
0
0
22
8
0
8
0
0
8
22
0
0
0
0
8
% K
% Leu:
8
0
0
0
0
8
72
8
8
0
0
0
8
0
0
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
8
8
0
22
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
8
0
0
0
0
72
0
8
0
0
0
0
% Q
% Arg:
0
0
43
8
0
0
0
0
0
0
0
0
8
0
8
% R
% Ser:
65
8
8
0
0
0
0
0
0
43
8
8
0
8
0
% S
% Thr:
0
0
0
0
0
0
0
72
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
8
8
0
0
0
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
15
79
8
0
0
8
0
72
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _