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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS18
All Species:
22.42
Human Site:
S373
Identified Species:
37.95
UniProt:
Q9P253
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P253
NP_065908.1
973
110186
S373
L
K
H
M
V
K
D
S
S
T
G
Q
L
W
A
Chimpanzee
Pan troglodytes
XP_523187
973
110161
S373
L
K
H
M
V
K
D
S
S
T
G
Q
L
W
A
Rhesus Macaque
Macaca mulatta
XP_001099146
973
110096
S373
L
K
H
M
V
K
D
S
S
T
G
Q
L
W
A
Dog
Lupus familis
XP_544627
1095
122945
S495
L
K
H
M
V
K
D
S
S
T
G
H
L
W
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8R307
973
110200
S373
L
R
H
M
V
K
D
S
S
T
G
H
L
W
A
Rat
Rattus norvegicus
NP_001099969
973
110167
S373
L
R
H
M
V
K
D
S
S
T
G
H
L
W
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506026
612
69591
F91
I
A
L
T
Q
F
H
F
L
L
L
L
A
D
R
Chicken
Gallus gallus
XP_421131
974
112556
P373
L
T
R
M
I
K
D
P
M
V
Q
Q
I
W
I
Frog
Xenopus laevis
NP_001085645
968
111576
P368
L
K
K
M
L
K
D
P
N
I
G
Q
I
W
I
Zebra Danio
Brachydanio rerio
P59015
974
113248
P373
L
Q
K
M
I
K
D
P
I
T
G
L
V
W
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24314
1002
115316
E402
P
L
S
I
E
R
D
E
L
T
G
S
I
Y
V
Honey Bee
Apis mellifera
XP_396968
718
83450
Y197
Y
E
K
S
A
L
I
Y
A
D
T
H
S
S
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_172709
994
113061
A348
I
I
G
L
C
S
D
A
S
A
N
V
F
Y
A
Baker's Yeast
Sacchar. cerevisiae
P27801
918
107380
P339
E
I
I
I
E
N
E
P
N
S
V
W
N
L
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99.6
86.6
N.A.
95.7
95.1
N.A.
52.8
74
68.3
65.9
N.A.
34.7
34.6
N.A.
N.A.
Protein Similarity:
100
99.9
99.9
87.4
N.A.
97.5
97.1
N.A.
56.4
86.4
83.2
82.4
N.A.
53.6
51.4
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
0
40
53.3
46.6
N.A.
20
0
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
6.6
53.3
73.3
66.6
N.A.
46.6
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
32.7
21.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.3
41.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
8
0
0
8
8
8
0
0
8
0
50
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
79
0
0
8
0
0
0
8
0
% D
% Glu:
8
8
0
0
15
0
8
8
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
8
0
8
0
0
0
0
8
0
8
% F
% Gly:
0
0
8
0
0
0
0
0
0
0
65
0
0
0
0
% G
% His:
0
0
43
0
0
0
8
0
0
0
0
29
0
0
0
% H
% Ile:
15
15
8
15
15
0
8
0
8
8
0
0
22
0
22
% I
% Lys:
0
36
22
0
0
65
0
0
0
0
0
0
0
0
0
% K
% Leu:
65
8
8
8
8
8
0
0
15
8
8
15
43
8
8
% L
% Met:
0
0
0
65
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
15
0
8
0
8
0
0
% N
% Pro:
8
0
0
0
0
0
0
29
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
0
8
0
0
0
0
0
8
36
0
0
0
% Q
% Arg:
0
15
8
0
0
8
0
0
0
0
0
0
0
0
8
% R
% Ser:
0
0
8
8
0
8
0
43
50
8
0
8
8
8
0
% S
% Thr:
0
8
0
8
0
0
0
0
0
58
8
0
0
0
0
% T
% Val:
0
0
0
0
43
0
0
0
0
8
8
8
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
65
0
% W
% Tyr:
8
0
0
0
0
0
0
8
0
0
0
0
0
15
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _