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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS18
All Species:
34.85
Human Site:
S177
Identified Species:
58.97
UniProt:
Q9P253
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P253
NP_065908.1
973
110186
S177
F
E
A
E
L
S
A
S
E
G
G
L
F
G
P
Chimpanzee
Pan troglodytes
XP_523187
973
110161
S177
F
E
A
E
L
S
A
S
E
G
G
L
F
G
P
Rhesus Macaque
Macaca mulatta
XP_001099146
973
110096
S177
F
E
A
E
L
S
A
S
E
G
G
L
F
G
P
Dog
Lupus familis
XP_544627
1095
122945
S299
F
E
A
E
L
S
A
S
E
G
G
L
F
G
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8R307
973
110200
S177
F
E
A
E
L
S
A
S
E
G
G
L
F
G
P
Rat
Rattus norvegicus
NP_001099969
973
110167
S177
F
E
A
E
L
S
A
S
E
G
G
L
F
G
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506026
612
69591
Chicken
Gallus gallus
XP_421131
974
112556
S177
Y
E
A
E
I
S
V
S
E
G
S
L
F
S
T
Frog
Xenopus laevis
NP_001085645
968
111576
S176
F
E
A
D
I
S
A
S
E
G
G
L
F
S
T
Zebra Danio
Brachydanio rerio
P59015
974
113248
S177
F
E
A
E
I
S
A
S
E
G
S
L
F
N
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24314
1002
115316
A202
F
E
T
E
L
N
P
A
A
D
G
H
V
Q
R
Honey Bee
Apis mellifera
XP_396968
718
83450
Y17
S
Y
S
K
I
Q
F
Y
Y
P
T
L
G
S
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_172709
994
113061
K153
D
E
K
D
K
R
E
K
Y
I
K
F
L
F
E
Baker's Yeast
Sacchar. cerevisiae
P27801
918
107380
W155
G
I
D
G
I
A
Y
W
E
G
S
L
L
L
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99.6
86.6
N.A.
95.7
95.1
N.A.
52.8
74
68.3
65.9
N.A.
34.7
34.6
N.A.
N.A.
Protein Similarity:
100
99.9
99.9
87.4
N.A.
97.5
97.1
N.A.
56.4
86.4
83.2
82.4
N.A.
53.6
51.4
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
0
60
73.3
73.3
N.A.
33.3
6.6
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
0
73.3
86.6
80
N.A.
46.6
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
32.7
21.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.3
41.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
65
0
0
8
58
8
8
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
8
15
0
0
0
0
0
8
0
0
0
0
0
% D
% Glu:
0
79
0
65
0
0
8
0
72
0
0
0
0
0
8
% E
% Phe:
65
0
0
0
0
0
8
0
0
0
0
8
65
8
0
% F
% Gly:
8
0
0
8
0
0
0
0
0
72
58
0
8
43
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
8
0
0
36
0
0
0
0
8
0
0
0
0
0
% I
% Lys:
0
0
8
8
8
0
0
8
0
0
8
0
0
0
0
% K
% Leu:
0
0
0
0
50
0
0
0
0
0
0
79
15
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
0
0
0
0
0
8
0
% N
% Pro:
0
0
0
0
0
0
8
0
0
8
0
0
0
0
43
% P
% Gln:
0
0
0
0
0
8
0
0
0
0
0
0
0
8
0
% Q
% Arg:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% R
% Ser:
8
0
8
0
0
65
0
65
0
0
22
0
0
22
0
% S
% Thr:
0
0
8
0
0
0
0
0
0
0
8
0
0
0
29
% T
% Val:
0
0
0
0
0
0
8
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
8
8
0
0
0
0
8
8
15
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _