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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCE1
All Species:
6.36
Human Site:
T1153
Identified Species:
20
UniProt:
Q9P212
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P212
NP_057425.3
2302
258715
T1153
S
R
R
A
H
S
L
T
T
A
G
S
P
N
L
Chimpanzee
Pan troglodytes
XP_001149565
2301
258406
T1153
S
R
R
A
H
S
L
T
T
A
G
S
P
N
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q8K4S1
2282
255002
R1144
P
P
N
P
L
H
S
R
R
A
Y
S
L
T
T
Rat
Rattus norvegicus
Q99P84
2281
255374
R1144
P
P
N
P
L
H
S
R
R
A
Y
S
L
T
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_426519
1366
151897
V286
R
A
P
R
K
V
K
V
A
C
S
G
H
S
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001155125
2248
250607
T1121
G
S
S
S
S
S
S
T
S
S
S
V
A
S
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392335
2406
271863
P1229
S
S
R
D
R
V
P
P
R
S
P
P
G
S
A
Nematode Worm
Caenorhab. elegans
NP_001129926
1878
210401
N798
S
R
L
A
S
V
S
N
S
Y
N
A
D
F
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
N.A.
N.A.
N.A.
84.8
84.2
N.A.
N.A.
40.7
N.A.
58.5
N.A.
N.A.
29.9
24.7
N.A.
Protein Similarity:
100
99.4
N.A.
N.A.
N.A.
90.8
90.5
N.A.
N.A.
47.4
N.A.
72
N.A.
N.A.
47.4
41.7
N.A.
P-Site Identity:
100
100
N.A.
N.A.
N.A.
13.3
13.3
N.A.
N.A.
0
N.A.
13.3
N.A.
N.A.
13.3
26.6
N.A.
P-Site Similarity:
100
100
N.A.
N.A.
N.A.
13.3
13.3
N.A.
N.A.
6.6
N.A.
40
N.A.
N.A.
26.6
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
13
0
38
0
0
0
0
13
50
0
13
13
0
13
% A
% Cys:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
0
% C
% Asp:
0
0
0
13
0
0
0
0
0
0
0
0
13
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
25
% F
% Gly:
13
0
0
0
0
0
0
0
0
0
25
13
13
0
0
% G
% His:
0
0
0
0
25
25
0
0
0
0
0
0
13
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
13
0
13
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
13
0
25
0
25
0
0
0
0
0
25
0
38
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
25
0
0
0
0
13
0
0
13
0
0
25
0
% N
% Pro:
25
25
13
25
0
0
13
13
0
0
13
13
25
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
13
38
38
13
13
0
0
25
38
0
0
0
0
0
0
% R
% Ser:
50
25
13
13
25
38
50
0
25
25
25
50
0
38
0
% S
% Thr:
0
0
0
0
0
0
0
38
25
0
0
0
0
25
25
% T
% Val:
0
0
0
0
0
38
0
13
0
0
0
13
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
13
25
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _