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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM63C
All Species:
18.79
Human Site:
Y525
Identified Species:
41.33
UniProt:
Q9P1W3
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P1W3
NP_065164.2
806
93317
Y525
R
W
L
F
D
I
Y
Y
L
E
Q
A
S
I
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001089796
853
97098
S585
R
W
L
F
D
K
T
S
S
K
A
S
I
R
L
Dog
Lupus familis
XP_547926
804
93648
Y524
R
W
L
F
D
I
Y
Y
L
E
Q
A
S
I
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8CBX0
802
92993
Y523
R
W
L
F
D
I
Y
Y
L
E
H
A
T
I
R
Rat
Rattus norvegicus
NP_001101515
802
92944
Y523
R
W
L
F
D
I
Y
Y
L
E
H
A
T
I
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512688
801
91795
S539
R
W
L
F
D
R
A
S
A
E
P
S
V
R
L
Chicken
Gallus gallus
XP_421286
830
95065
F543
R
W
L
F
D
T
H
F
L
D
Q
A
D
I
K
Frog
Xenopus laevis
NP_001088752
803
91863
L539
R
W
L
F
D
R
A
L
D
Q
Q
G
S
V
R
Zebra Danio
Brachydanio rerio
NP_001153308
796
91478
L531
L
N
L
F
F
R
W
L
F
D
V
R
F
L
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392828
767
85105
S504
L
P
S
L
G
L
T
S
A
Q
A
F
L
E
W
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785977
734
83832
Y473
L
L
V
V
Y
S
S
Y
Y
F
E
F
H
W
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
35.7
84.9
N.A.
83.6
82.8
N.A.
41.9
57.3
44.1
52.9
N.A.
N.A.
32.7
N.A.
35.7
Protein Similarity:
100
N.A.
54.1
93.3
N.A.
91.8
91.8
N.A.
62.9
75.1
62.6
73.3
N.A.
N.A.
52.3
N.A.
55.5
P-Site Identity:
100
N.A.
33.3
100
N.A.
86.6
86.6
N.A.
40
60
53.3
13.3
N.A.
N.A.
0
N.A.
6.6
P-Site Similarity:
100
N.A.
46.6
100
N.A.
93.3
93.3
N.A.
46.6
86.6
66.6
33.3
N.A.
N.A.
13.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
19
0
19
0
19
46
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
73
0
0
0
10
19
0
0
10
0
10
% D
% Glu:
0
0
0
0
0
0
0
0
0
46
10
0
0
10
0
% E
% Phe:
0
0
0
82
10
0
0
10
10
10
0
19
10
0
0
% F
% Gly:
0
0
0
0
10
0
0
0
0
0
0
10
0
0
0
% G
% His:
0
0
0
0
0
0
10
0
0
0
19
0
10
0
0
% H
% Ile:
0
0
0
0
0
37
0
0
0
0
0
0
10
46
0
% I
% Lys:
0
0
0
0
0
10
0
0
0
10
0
0
0
0
10
% K
% Leu:
28
10
82
10
0
10
0
19
46
0
0
0
10
10
19
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
0
0
0
0
0
0
0
0
10
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
19
37
0
0
0
0
% Q
% Arg:
73
0
0
0
0
28
0
0
0
0
0
10
0
19
46
% R
% Ser:
0
0
10
0
0
10
10
28
10
0
0
19
28
0
0
% S
% Thr:
0
0
0
0
0
10
19
0
0
0
0
0
19
0
10
% T
% Val:
0
0
10
10
0
0
0
0
0
0
10
0
10
10
0
% V
% Trp:
0
73
0
0
0
0
10
0
0
0
0
0
0
10
10
% W
% Tyr:
0
0
0
0
10
0
37
46
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _