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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM63C
All Species:
7.27
Human Site:
S731
Identified Species:
16
UniProt:
Q9P1W3
Number Species:
10
Phosphosite Substitution
Charge Score:
0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P1W3
NP_065164.2
806
93317
S731
T
V
F
D
M
E
P
S
S
T
S
S
T
P
T
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001089796
853
97098
E779
S
P
L
N
Y
K
T
E
E
P
A
S
D
K
G
Dog
Lupus familis
XP_547926
804
93648
S729
T
V
F
D
M
E
P
S
S
T
S
S
T
P
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8CBX0
802
92993
E727
T
E
T
V
F
D
V
E
P
S
S
T
T
S
T
Rat
Rattus norvegicus
NP_001101515
802
92944
E727
T
E
T
V
F
D
V
E
P
S
S
T
T
S
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512688
801
91795
P727
S
C
F
K
H
L
S
P
L
N
Y
K
I
D
D
Chicken
Gallus gallus
XP_421286
830
95065
S751
S
F
A
D
A
E
R
S
S
V
S
S
T
P
N
Frog
Xenopus laevis
NP_001088752
803
91863
M729
C
F
R
H
L
N
P
M
N
Y
K
I
E
E
K
Zebra Danio
Brachydanio rerio
NP_001153308
796
91478
L720
F
G
F
C
L
K
K
L
R
A
D
R
S
T
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392828
767
85105
A692
I
L
G
L
V
T
G
A
T
L
S
T
S
K
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785977
734
83832
V660
Q
S
A
V
N
F
V
V
I
A
G
M
L
L
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
35.7
84.9
N.A.
83.6
82.8
N.A.
41.9
57.3
44.1
52.9
N.A.
N.A.
32.7
N.A.
35.7
Protein Similarity:
100
N.A.
54.1
93.3
N.A.
91.8
91.8
N.A.
62.9
75.1
62.6
73.3
N.A.
N.A.
52.3
N.A.
55.5
P-Site Identity:
100
N.A.
6.6
100
N.A.
26.6
26.6
N.A.
6.6
53.3
6.6
6.6
N.A.
N.A.
6.6
N.A.
0
P-Site Similarity:
100
N.A.
33.3
100
N.A.
46.6
46.6
N.A.
13.3
60
20
33.3
N.A.
N.A.
46.6
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
19
0
10
0
0
10
0
19
10
0
0
0
0
% A
% Cys:
10
10
0
10
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
28
0
19
0
0
0
0
10
0
10
10
10
% D
% Glu:
0
19
0
0
0
28
0
28
10
0
0
0
10
10
0
% E
% Phe:
10
19
37
0
19
10
0
0
0
0
0
0
0
0
10
% F
% Gly:
0
10
10
0
0
0
10
0
0
0
10
0
0
0
10
% G
% His:
0
0
0
10
10
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
0
0
10
0
0
10
10
0
0
% I
% Lys:
0
0
0
10
0
19
10
0
0
0
10
10
0
19
10
% K
% Leu:
0
10
10
10
19
10
0
10
10
10
0
0
10
10
0
% L
% Met:
0
0
0
0
19
0
0
10
0
0
0
10
0
0
0
% M
% Asn:
0
0
0
10
10
10
0
0
10
10
0
0
0
0
10
% N
% Pro:
0
10
0
0
0
0
28
10
19
10
0
0
0
28
0
% P
% Gln:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% Q
% Arg:
0
0
10
0
0
0
10
0
10
0
0
10
0
0
0
% R
% Ser:
28
10
0
0
0
0
10
28
28
19
55
37
19
19
10
% S
% Thr:
37
0
19
0
0
10
10
0
10
19
0
28
46
10
37
% T
% Val:
0
19
0
28
10
0
28
10
0
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
0
0
10
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _