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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMEM63C All Species: 9.09
Human Site: S25 Identified Species: 20
UniProt: Q9P1W3 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P1W3 NP_065164.2 806 93317 S25 T V D E C F Q S R N T V L Q G
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001089796 853 97098 S65 P F L E L W Q S K A V S I R E
Dog Lupus familis XP_547926 804 93648 R25 T D E C F Q S R S T V L Q G Q
Cat Felis silvestris
Mouse Mus musculus Q8CBX0 802 92993 S25 N E C F Q S R S T V L Q G Q P
Rat Rattus norvegicus NP_001101515 802 92944 S25 N E C F Q S R S T V L Q G Q P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512688 801 91795 R39 S Y C Y S T A R E S T V L Q G
Chicken Gallus gallus XP_421286 830 95065 S41 E Q C F S A R S R S T V L Q G
Frog Xenopus laevis NP_001088752 803 91863 N25 W I S G P L F N Q S N D S Q S
Zebra Danio Brachydanio rerio NP_001153308 796 91478 S38 E R C Y R S H S R S S V L Q G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392828 767 85105 H28 T C I P I P R H N S T I I L P
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785977 734 83832
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 35.7 84.9 N.A. 83.6 82.8 N.A. 41.9 57.3 44.1 52.9 N.A. N.A. 32.7 N.A. 35.7
Protein Similarity: 100 N.A. 54.1 93.3 N.A. 91.8 91.8 N.A. 62.9 75.1 62.6 73.3 N.A. N.A. 52.3 N.A. 55.5
P-Site Identity: 100 N.A. 20 6.6 N.A. 13.3 13.3 N.A. 33.3 46.6 6.6 40 N.A. N.A. 13.3 N.A. 0
P-Site Similarity: 100 N.A. 46.6 20 N.A. 20 20 N.A. 46.6 60 33.3 53.3 N.A. N.A. 40 N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 10 10 0 0 10 0 0 0 0 0 % A
% Cys: 0 10 46 10 10 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 10 0 0 0 0 0 0 0 0 10 0 0 0 % D
% Glu: 19 19 10 19 0 0 0 0 10 0 0 0 0 0 10 % E
% Phe: 0 10 0 28 10 10 10 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 10 0 0 0 0 0 0 0 0 19 10 37 % G
% His: 0 0 0 0 0 0 10 10 0 0 0 0 0 0 0 % H
% Ile: 0 10 10 0 10 0 0 0 0 0 0 10 19 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % K
% Leu: 0 0 10 0 10 10 0 0 0 0 19 10 37 10 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 19 0 0 0 0 0 0 10 10 10 10 0 0 0 0 % N
% Pro: 10 0 0 10 10 10 0 0 0 0 0 0 0 0 28 % P
% Gln: 0 10 0 0 19 10 19 0 10 0 0 19 10 64 10 % Q
% Arg: 0 10 0 0 10 0 37 19 28 0 0 0 0 10 0 % R
% Ser: 10 0 10 0 19 28 10 55 10 46 10 10 10 0 10 % S
% Thr: 28 0 0 0 0 10 0 0 19 10 37 0 0 0 0 % T
% Val: 0 10 0 0 0 0 0 0 0 19 19 37 0 0 0 % V
% Trp: 10 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 0 19 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _