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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CACNA1I
All Species:
10.3
Human Site:
Y457
Identified Species:
28.33
UniProt:
Q9P0X4
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P0X4
NP_001003406.1
2223
245103
Y457
K
R
R
A
L
G
L
Y
Q
A
L
Q
S
R
R
Chimpanzee
Pan troglodytes
XP_001166127
2229
245998
Y458
K
R
R
A
L
G
L
Y
Q
A
L
Q
S
R
R
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_538364
2184
240837
L456
A
R
R
R
A
L
G
L
Y
Q
A
L
Q
S
R
Cat
Felis silvestris
Mouse
Mus musculus
O88427
2365
261928
Y479
K
R
R
S
L
R
L
Y
A
R
W
Q
S
R
W
Rat
Rattus norvegicus
Q9Z0Y8
2201
243675
Y426
S
S
S
T
V
A
S
Y
A
E
P
G
D
C
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_425474
2192
245395
A441
Y
L
S
S
S
T
V
A
S
Y
M
E
P
G
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q2XVR3
1829
207718
E313
K
A
Y
I
N
N
E
E
N
Q
Y
F
L
E
G
Tiger Blowfish
Takifugu rubipres
Q2XVR7
1892
213080
L376
D
S
F
G
W
A
F
L
A
L
F
R
L
M
T
Fruit Fly
Dros. melanogaster
Q9W0Y8
2821
318606
Y454
K
G
V
L
L
A
S
Y
S
K
K
K
T
R
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.1
N.A.
90.5
N.A.
53.7
92
N.A.
N.A.
77.9
N.A.
24.8
24.5
20.7
N.A.
N.A.
N.A.
Protein Similarity:
100
97.6
N.A.
92.2
N.A.
64
93.5
N.A.
N.A.
83.8
N.A.
42.8
42.9
37.5
N.A.
N.A.
N.A.
P-Site Identity:
100
100
N.A.
20
N.A.
60
6.6
N.A.
N.A.
0
N.A.
6.6
0
33.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
20
N.A.
66.6
13.3
N.A.
N.A.
26.6
N.A.
6.6
6.6
46.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
12
0
23
12
34
0
12
34
23
12
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% C
% Asp:
12
0
0
0
0
0
0
0
0
0
0
0
12
0
12
% D
% Glu:
0
0
0
0
0
0
12
12
0
12
0
12
0
12
0
% E
% Phe:
0
0
12
0
0
0
12
0
0
0
12
12
0
0
0
% F
% Gly:
0
12
0
12
0
23
12
0
0
0
0
12
0
12
12
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
56
0
0
0
0
0
0
0
0
12
12
12
0
0
0
% K
% Leu:
0
12
0
12
45
12
34
23
0
12
23
12
23
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
12
0
0
12
0
% M
% Asn:
0
0
0
0
12
12
0
0
12
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
12
0
12
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
23
23
0
34
12
0
0
% Q
% Arg:
0
45
45
12
0
12
0
0
0
12
0
12
0
45
45
% R
% Ser:
12
23
23
23
12
0
23
0
23
0
0
0
34
12
0
% S
% Thr:
0
0
0
12
0
12
0
0
0
0
0
0
12
0
12
% T
% Val:
0
0
12
0
12
0
12
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
12
0
0
0
0
0
12
0
0
0
12
% W
% Tyr:
12
0
12
0
0
0
0
56
12
12
12
0
0
0
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _