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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEPT10 All Species: 4.24
Human Site: S40 Identified Species: 7.78
UniProt: Q9P0V9 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P0V9 NP_653311.1 454 52593 S40 I K R E N I R S L T M S G H V
Chimpanzee Pan troglodytes Q5R1W1 434 50272 E76 L T D L Y S P E Y P G P S H R
Rhesus Macaque Macaca mulatta XP_001085213 523 60991 S40 R K R E N V R S L T M S G H V
Dog Lupus familis XP_540501 432 50596 H40 F G F E C L P H Q L V N R S I
Cat Felis silvestris
Mouse Mus musculus Q8C650 452 52404 R77 S H F C P C V R L R A Q T Y E
Rat Rattus norvegicus Q5PQK1 456 53020 R81 S H F C P C V R L R A Q T Y E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510590 457 52831 G41 L S L G G H V G F D S L P D Q
Chicken Gallus gallus Q5ZMH1 349 40206 K9 S Q S G E K V K F S D S A G Y
Frog Xenopus laevis Q6IRQ5 427 49743 F67 N T L F N T T F E T E E A S H
Zebra Danio Brachydanio rerio A4FUM1 423 49080 H80 S H F H N G V H L R P R T Y S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P54359 419 48456 M47 N G F V F N V M C I G E T G L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_790953 437 50335 L43 G H V G F D S L P D Q L V N K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32457 520 60021 F118 R R S I K N G F S F N L L C V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 40.9 77.6 70 N.A. 81.2 81.5 N.A. 69.1 34.7 70 66.9 N.A. 62.7 N.A. N.A. 64.9
Protein Similarity: 100 61.2 81.2 82.1 N.A. 90.3 89.9 N.A. 82.7 53.7 81.5 80.4 N.A. 77 N.A. N.A. 78.8
P-Site Identity: 100 6.6 86.6 6.6 N.A. 6.6 6.6 N.A. 0 6.6 13.3 13.3 N.A. 0 N.A. N.A. 0
P-Site Similarity: 100 13.3 93.3 33.3 N.A. 13.3 13.3 N.A. 6.6 20 13.3 20 N.A. 6.6 N.A. N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 33.8 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 51.9 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 16 0 16 0 0 % A
% Cys: 0 0 0 16 8 16 0 0 8 0 0 0 0 8 0 % C
% Asp: 0 0 8 0 0 8 0 0 0 16 8 0 0 8 0 % D
% Glu: 0 0 0 24 8 0 0 8 8 0 8 16 0 0 16 % E
% Phe: 8 0 39 8 16 0 0 16 16 8 0 0 0 0 0 % F
% Gly: 8 16 0 24 8 8 8 8 0 0 16 0 16 16 0 % G
% His: 0 31 0 8 0 8 0 16 0 0 0 0 0 24 8 % H
% Ile: 8 0 0 8 0 8 0 0 0 8 0 0 0 0 8 % I
% Lys: 0 16 0 0 8 8 0 8 0 0 0 0 0 0 8 % K
% Leu: 16 0 16 8 0 8 0 8 39 8 0 24 8 0 8 % L
% Met: 0 0 0 0 0 0 0 8 0 0 16 0 0 0 0 % M
% Asn: 16 0 0 0 31 16 0 0 0 0 8 8 0 8 0 % N
% Pro: 0 0 0 0 16 0 16 0 8 8 8 8 8 0 0 % P
% Gln: 0 8 0 0 0 0 0 0 8 0 8 16 0 0 8 % Q
% Arg: 16 8 16 0 0 0 16 16 0 24 0 8 8 0 8 % R
% Ser: 31 8 16 0 0 8 8 16 8 8 8 24 8 16 8 % S
% Thr: 0 16 0 0 0 8 8 0 0 24 0 0 31 0 0 % T
% Val: 0 0 8 8 0 8 47 0 0 0 8 0 8 0 24 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 0 0 0 8 0 0 0 0 24 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _