KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CXXC1
All Species:
22.42
Human Site:
Y69
Identified Species:
49.33
UniProt:
Q9P0U4
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P0U4
NP_001095124.1
656
75712
Y69
A
K
A
I
R
E
W
Y
C
R
E
C
R
E
K
Chimpanzee
Pan troglodytes
XP_001153829
617
71510
D54
H
K
K
S
R
E
R
D
G
N
E
R
D
S
S
Rhesus Macaque
Macaca mulatta
XP_001093242
656
75633
Y69
A
K
A
I
R
E
W
Y
C
R
E
C
R
E
K
Dog
Lupus familis
XP_850188
656
75587
Y69
A
K
A
I
R
E
W
Y
C
R
E
C
R
E
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9CWW7
660
76149
Y69
A
K
A
I
R
E
W
Y
C
R
E
C
R
E
K
Rat
Rattus norvegicus
NP_001073166
660
76255
Y69
A
K
A
I
R
E
W
Y
C
R
E
C
R
E
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521007
954
110930
Y386
A
K
A
I
R
E
W
Y
C
L
Q
C
R
E
K
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001085408
576
67738
A61
I
T
E
K
M
A
K
A
I
R
E
W
Y
C
M
Zebra Danio
Brachydanio rerio
NP_956627
563
66569
I54
E
W
F
H
G
H
C
I
N
V
T
E
K
M
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_394738
518
61069
E22
A
K
Q
F
M
L
P
E
R
K
S
K
I
A
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001196775
593
67745
Q54
F
T
I
L
P
E
R
Q
A
K
V
A
T
L
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94
99.6
98.9
N.A.
96.2
96.2
N.A.
53.4
N.A.
69.8
62.6
N.A.
N.A.
39
N.A.
33.9
Protein Similarity:
100
94
99.6
98.9
N.A.
96.9
96.9
N.A.
59.6
N.A.
79.4
72.7
N.A.
N.A.
53.6
N.A.
52.9
P-Site Identity:
100
26.6
100
100
N.A.
100
100
N.A.
86.6
N.A.
13.3
0
N.A.
N.A.
13.3
N.A.
6.6
P-Site Similarity:
100
26.6
100
100
N.A.
100
100
N.A.
93.3
N.A.
13.3
6.6
N.A.
N.A.
20
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
64
0
55
0
0
10
0
10
10
0
0
10
0
10
10
% A
% Cys:
0
0
0
0
0
0
10
0
55
0
0
55
0
10
0
% C
% Asp:
0
0
0
0
0
0
0
10
0
0
0
0
10
0
0
% D
% Glu:
10
0
10
0
0
73
0
10
0
0
64
10
0
55
0
% E
% Phe:
10
0
10
10
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
10
0
0
0
10
0
0
0
0
0
0
% G
% His:
10
0
0
10
0
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
10
55
0
0
0
10
10
0
0
0
10
0
0
% I
% Lys:
0
73
10
10
0
0
10
0
0
19
0
10
10
0
55
% K
% Leu:
0
0
0
10
0
10
0
0
0
10
0
0
0
10
0
% L
% Met:
0
0
0
0
19
0
0
0
0
0
0
0
0
10
10
% M
% Asn:
0
0
0
0
0
0
0
0
10
10
0
0
0
0
0
% N
% Pro:
0
0
0
0
10
0
10
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
10
0
0
0
0
10
0
0
10
0
0
0
0
% Q
% Arg:
0
0
0
0
64
0
19
0
10
55
0
10
55
0
0
% R
% Ser:
0
0
0
10
0
0
0
0
0
0
10
0
0
10
10
% S
% Thr:
0
19
0
0
0
0
0
0
0
0
10
0
10
0
10
% T
% Val:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
10
% V
% Trp:
0
10
0
0
0
0
55
0
0
0
0
10
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
55
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _