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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CXXC1 All Species: 20.3
Human Site: T126 Identified Species: 44.67
UniProt: Q9P0U4 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P0U4 NP_001095124.1 656 75712 T126 Q R R A G S G T G V G A M L A
Chimpanzee Pan troglodytes XP_001153829 617 71510 K102 R G S A S P H K S S P Q P L V
Rhesus Macaque Macaca mulatta XP_001093242 656 75633 T126 Q R R A G S G T G V G A M L A
Dog Lupus familis XP_850188 656 75587 T126 Q R R A G S G T G V G A M L A
Cat Felis silvestris
Mouse Mus musculus Q9CWW7 660 76149 T126 Q R R A G S G T G V G A M L A
Rat Rattus norvegicus NP_001073166 660 76255 T126 Q R R A G S G T G V G A M L A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521007 954 110930 G439 Q R R A G A K G F D R G S I Q
Chicken Gallus gallus
Frog Xenopus laevis NP_001085408 576 67738 S109 T K N E K K K S S T S S N K V
Zebra Danio Brachydanio rerio NP_956627 563 66569 S102 E R V E K R S S T P E Y K I D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_394738 518 61069 K70 D C I N I T E K D A K H I K Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001196775 593 67745 M102 L D D N G E P M A Y C L C R S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94 99.6 98.9 N.A. 96.2 96.2 N.A. 53.4 N.A. 69.8 62.6 N.A. N.A. 39 N.A. 33.9
Protein Similarity: 100 94 99.6 98.9 N.A. 96.9 96.9 N.A. 59.6 N.A. 79.4 72.7 N.A. N.A. 53.6 N.A. 52.9
P-Site Identity: 100 13.3 100 100 N.A. 100 100 N.A. 33.3 N.A. 0 6.6 N.A. N.A. 0 N.A. 6.6
P-Site Similarity: 100 20 100 100 N.A. 100 100 N.A. 46.6 N.A. 20 26.6 N.A. N.A. 13.3 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 64 0 10 0 0 10 10 0 46 0 0 46 % A
% Cys: 0 10 0 0 0 0 0 0 0 0 10 0 10 0 0 % C
% Asp: 10 10 10 0 0 0 0 0 10 10 0 0 0 0 10 % D
% Glu: 10 0 0 19 0 10 10 0 0 0 10 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % F
% Gly: 0 10 0 0 64 0 46 10 46 0 46 10 0 0 0 % G
% His: 0 0 0 0 0 0 10 0 0 0 0 10 0 0 0 % H
% Ile: 0 0 10 0 10 0 0 0 0 0 0 0 10 19 0 % I
% Lys: 0 10 0 0 19 10 19 19 0 0 10 0 10 19 0 % K
% Leu: 10 0 0 0 0 0 0 0 0 0 0 10 0 55 0 % L
% Met: 0 0 0 0 0 0 0 10 0 0 0 0 46 0 0 % M
% Asn: 0 0 10 19 0 0 0 0 0 0 0 0 10 0 0 % N
% Pro: 0 0 0 0 0 10 10 0 0 10 10 0 10 0 0 % P
% Gln: 55 0 0 0 0 0 0 0 0 0 0 10 0 0 19 % Q
% Arg: 10 64 55 0 0 10 0 0 0 0 10 0 0 10 0 % R
% Ser: 0 0 10 0 10 46 10 19 19 10 10 10 10 0 10 % S
% Thr: 10 0 0 0 0 10 0 46 10 10 0 0 0 0 0 % T
% Val: 0 0 10 0 0 0 0 0 0 46 0 0 0 0 19 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 10 0 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _