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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CXXC1
All Species:
23.33
Human Site:
S248
Identified Species:
51.33
UniProt:
Q9P0U4
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P0U4
NP_001095124.1
656
75712
S248
T
Q
Q
Q
P
Q
P
S
Q
K
L
G
R
I
R
Chimpanzee
Pan troglodytes
XP_001153829
617
71510
S209
T
Q
Q
Q
P
Q
P
S
Q
K
L
G
R
I
R
Rhesus Macaque
Macaca mulatta
XP_001093242
656
75633
S248
T
Q
Q
Q
P
Q
P
S
Q
K
L
G
R
I
R
Dog
Lupus familis
XP_850188
656
75587
S248
T
Q
Q
Q
P
Q
P
S
Q
K
L
G
R
I
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9CWW7
660
76149
S252
T
Q
Q
Q
P
Q
Q
S
Q
K
L
G
R
I
R
Rat
Rattus norvegicus
NP_001073166
660
76255
S253
T
Q
Q
Q
P
Q
Q
S
Q
K
L
G
R
I
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521007
954
110930
L546
R
V
L
P
C
V
F
L
R
Q
P
P
W
K
M
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001085408
576
67738
L209
D
L
P
L
D
P
E
L
Y
Q
E
L
C
A
G
Zebra Danio
Brachydanio rerio
NP_956627
563
66569
M202
D
D
Y
D
E
N
D
M
D
L
Y
E
H
Y
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_394738
518
61069
C170
S
V
R
L
K
L
R
C
I
Q
R
T
C
R
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001196775
593
67745
S202
A
A
Q
N
R
S
N
S
V
Q
L
L
N
H
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94
99.6
98.9
N.A.
96.2
96.2
N.A.
53.4
N.A.
69.8
62.6
N.A.
N.A.
39
N.A.
33.9
Protein Similarity:
100
94
99.6
98.9
N.A.
96.9
96.9
N.A.
59.6
N.A.
79.4
72.7
N.A.
N.A.
53.6
N.A.
52.9
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
0
N.A.
0
0
N.A.
N.A.
0
N.A.
20
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
13.3
N.A.
6.6
6.6
N.A.
N.A.
20
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
0
0
0
0
0
0
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
10
0
0
10
0
0
0
0
19
0
0
% C
% Asp:
19
10
0
10
10
0
10
0
10
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
10
0
10
0
0
0
10
10
0
0
0
% E
% Phe:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
55
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
10
10
10
% H
% Ile:
0
0
0
0
0
0
0
0
10
0
0
0
0
55
0
% I
% Lys:
0
0
0
0
10
0
0
0
0
55
0
0
0
10
10
% K
% Leu:
0
10
10
19
0
10
0
19
0
10
64
19
0
0
0
% L
% Met:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
10
% M
% Asn:
0
0
0
10
0
10
10
0
0
0
0
0
10
0
0
% N
% Pro:
0
0
10
10
55
10
37
0
0
0
10
10
0
0
0
% P
% Gln:
0
55
64
55
0
55
19
0
55
37
0
0
0
0
0
% Q
% Arg:
10
0
10
0
10
0
10
0
10
0
10
0
55
10
55
% R
% Ser:
10
0
0
0
0
10
0
64
0
0
0
0
0
0
0
% S
% Thr:
55
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% T
% Val:
0
19
0
0
0
10
0
0
10
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% W
% Tyr:
0
0
10
0
0
0
0
0
10
0
10
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _