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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CXXC1
All Species:
23.33
Human Site:
S221
Identified Species:
51.33
UniProt:
Q9P0U4
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P0U4
NP_001095124.1
656
75712
S221
E
S
Y
K
Y
F
P
S
S
L
S
P
V
T
P
Chimpanzee
Pan troglodytes
XP_001153829
617
71510
S182
E
S
Y
K
Y
F
P
S
S
L
S
P
V
T
P
Rhesus Macaque
Macaca mulatta
XP_001093242
656
75633
S221
E
S
Y
K
Y
F
P
S
S
L
S
P
V
T
P
Dog
Lupus familis
XP_850188
656
75587
S221
E
S
Y
K
Y
F
P
S
S
L
S
P
V
T
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9CWW7
660
76149
S225
E
S
Y
K
Y
F
P
S
S
L
S
P
V
T
P
Rat
Rattus norvegicus
NP_001073166
660
76255
S226
E
S
Y
K
Y
F
P
S
S
L
S
P
V
T
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521007
954
110930
A519
L
R
Q
C
Q
L
R
A
R
E
S
Y
K
Y
F
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001085408
576
67738
L182
L
R
V
K
D
D
D
L
S
M
Y
R
D
T
P
Zebra Danio
Brachydanio rerio
NP_956627
563
66569
E175
K
M
L
R
V
R
D
E
E
F
S
L
R
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_394738
518
61069
L143
C
G
E
C
T
G
C
L
R
T
E
N
C
G
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001196775
593
67745
S175
S
G
E
K
T
G
A
S
E
A
D
A
S
G
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94
99.6
98.9
N.A.
96.2
96.2
N.A.
53.4
N.A.
69.8
62.6
N.A.
N.A.
39
N.A.
33.9
Protein Similarity:
100
94
99.6
98.9
N.A.
96.9
96.9
N.A.
59.6
N.A.
79.4
72.7
N.A.
N.A.
53.6
N.A.
52.9
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
6.6
N.A.
26.6
6.6
N.A.
N.A.
0
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
13.3
N.A.
33.3
20
N.A.
N.A.
0
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
10
0
10
0
10
0
0
0
% A
% Cys:
10
0
0
19
0
0
10
0
0
0
0
0
10
0
0
% C
% Asp:
0
0
0
0
10
10
19
0
0
0
10
0
10
0
10
% D
% Glu:
55
0
19
0
0
0
0
10
19
10
10
0
0
10
0
% E
% Phe:
0
0
0
0
0
55
0
0
0
10
0
0
0
0
10
% F
% Gly:
0
19
0
0
0
19
0
0
0
0
0
0
0
19
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
0
0
73
0
0
0
0
0
0
0
0
10
0
10
% K
% Leu:
19
0
10
0
0
10
0
19
0
55
0
10
0
0
0
% L
% Met:
0
10
0
0
0
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% N
% Pro:
0
0
0
0
0
0
55
0
0
0
0
55
0
0
64
% P
% Gln:
0
0
10
0
10
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
19
0
10
0
10
10
0
19
0
0
10
10
0
10
% R
% Ser:
10
55
0
0
0
0
0
64
64
0
73
0
10
0
0
% S
% Thr:
0
0
0
0
19
0
0
0
0
10
0
0
0
64
0
% T
% Val:
0
0
10
0
10
0
0
0
0
0
0
0
55
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
55
0
55
0
0
0
0
0
10
10
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _