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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHMP5
All Species:
34.55
Human Site:
Y45
Identified Species:
54.29
UniProt:
Q9NZZ3
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NZZ3
NP_057494.3
219
24571
Y45
L
D
A
E
L
V
K
Y
K
D
Q
I
K
K
M
Chimpanzee
Pan troglodytes
XP_001154646
234
26437
Y60
L
D
A
E
L
V
K
Y
K
D
Q
I
K
K
M
Rhesus Macaque
Macaca mulatta
XP_001100290
171
19502
L38
I
D
K
K
I
S
R
L
D
A
E
L
V
K
Y
Dog
Lupus familis
XP_531972
172
20255
L38
I
D
K
K
I
S
R
L
D
A
E
L
V
K
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q9D7S9
219
24557
Y45
L
D
A
E
L
V
K
Y
K
D
Q
I
K
K
M
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516973
195
21998
K38
G
P
A
K
N
M
V
K
Q
K
A
L
R
V
L
Chicken
Gallus gallus
XP_419052
219
24583
Y45
L
D
A
E
L
V
K
Y
K
D
Q
M
K
K
M
Frog
Xenopus laevis
Q6DD52
219
24768
Y45
L
D
A
E
L
I
K
Y
K
D
Q
M
K
K
M
Zebra Danio
Brachydanio rerio
Q7T339
220
24750
Y45
L
D
A
E
L
M
K
Y
K
D
Q
M
K
K
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVI9
226
25133
Y45
L
E
A
E
L
R
K
Y
R
E
Q
M
S
K
M
Honey Bee
Apis mellifera
XP_392468
221
24589
Y45
L
D
A
E
L
K
K
Y
K
D
Q
M
A
K
M
Nematode Worm
Caenorhab. elegans
NP_505219
217
24627
L44
L
D
Q
D
L
M
K
L
R
D
Q
M
S
K
M
Sea Urchin
Strong. purpuratus
XP_786663
219
24560
Y45
L
D
V
E
L
K
K
Y
K
D
Q
M
K
R
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O82197
213
23996
A41
E
N
V
L
L
K
K
A
T
G
E
V
E
K
A
Baker's Yeast
Sacchar. cerevisiae
Q03390
229
25843
L45
L
D
T
Q
I
A
Q
L
N
F
Q
L
Q
N
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.7
77.1
63
N.A.
98.6
N.A.
N.A.
85.3
93.6
89.5
84.5
N.A.
62.3
69.2
60.2
72.1
Protein Similarity:
100
88.4
78
70.3
N.A.
99
N.A.
N.A.
88.1
98.1
96.3
93.6
N.A.
76.1
83.7
79
85.8
P-Site Identity:
100
100
13.3
13.3
N.A.
100
N.A.
N.A.
6.6
93.3
86.6
86.6
N.A.
60
80
53.3
73.3
P-Site Similarity:
100
100
53.3
53.3
N.A.
100
N.A.
N.A.
46.6
100
100
100
N.A.
86.6
86.6
80
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
31
27.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.9
55.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
60
0
0
7
0
7
0
14
7
0
7
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
80
0
7
0
0
0
0
14
60
0
0
0
0
0
% D
% Glu:
7
7
0
60
0
0
0
0
0
7
20
0
7
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% F
% Gly:
7
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
14
0
0
0
20
7
0
0
0
0
0
20
0
0
7
% I
% Lys:
0
0
14
20
0
20
74
7
54
7
0
0
47
80
0
% K
% Leu:
74
0
0
7
74
0
0
27
0
0
0
27
0
0
7
% L
% Met:
0
0
0
0
0
20
0
0
0
0
0
47
0
0
67
% M
% Asn:
0
7
0
0
7
0
0
0
7
0
0
0
0
7
0
% N
% Pro:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
7
7
0
0
7
0
7
0
74
0
7
0
0
% Q
% Arg:
0
0
0
0
0
7
14
0
14
0
0
0
7
7
0
% R
% Ser:
0
0
0
0
0
14
0
0
0
0
0
0
14
0
0
% S
% Thr:
0
0
7
0
0
0
0
0
7
0
0
0
0
0
0
% T
% Val:
0
0
14
0
0
27
7
0
0
0
0
7
14
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
60
0
0
0
0
0
0
14
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _