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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHMP5
All Species:
40.61
Human Site:
Y182
Identified Species:
63.81
UniProt:
Q9NZZ3
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NZZ3
NP_057494.3
219
24571
Y182
L
A
D
E
D
S
S
Y
L
D
E
A
A
S
A
Chimpanzee
Pan troglodytes
XP_001154646
234
26437
Y197
L
A
D
E
D
S
S
Y
L
D
E
A
A
S
A
Rhesus Macaque
Macaca mulatta
XP_001100290
171
19502
M139
Q
D
Q
L
E
D
M
M
E
D
A
N
E
I
Q
Dog
Lupus familis
XP_531972
172
20255
F140
H
L
Q
F
Q
K
A
F
P
L
T
Q
R
I
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9D7S9
219
24557
Y182
L
A
D
E
D
S
S
Y
L
D
E
A
A
S
A
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516973
195
21998
Y158
L
A
D
E
D
T
S
Y
L
D
E
A
A
S
A
Chicken
Gallus gallus
XP_419052
219
24583
Y182
L
A
D
E
D
N
S
Y
L
D
E
A
A
S
A
Frog
Xenopus laevis
Q6DD52
219
24768
Y182
L
L
D
D
D
T
S
Y
L
D
E
A
A
S
A
Zebra Danio
Brachydanio rerio
Q7T339
220
24750
Y182
L
L
D
D
D
N
S
Y
L
D
E
A
S
S
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVI9
226
25133
Y182
A
L
D
D
D
T
S
Y
L
D
D
V
V
K
A
Honey Bee
Apis mellifera
XP_392468
221
24589
Y182
A
I
D
E
D
T
S
Y
L
D
D
A
I
K
A
Nematode Worm
Caenorhab. elegans
NP_505219
217
24627
Y182
I
G
E
S
D
T
N
Y
L
D
E
A
L
A
A
Sea Urchin
Strong. purpuratus
XP_786663
219
24560
Y182
L
M
D
D
D
T
S
Y
L
D
E
A
V
N
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O82197
213
23996
E169
L
D
E
L
E
G
A
E
L
E
E
Q
L
L
Q
Baker's Yeast
Sacchar. cerevisiae
Q03390
229
25843
A179
D
A
E
L
D
A
L
A
Q
E
D
F
T
L
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.7
77.1
63
N.A.
98.6
N.A.
N.A.
85.3
93.6
89.5
84.5
N.A.
62.3
69.2
60.2
72.1
Protein Similarity:
100
88.4
78
70.3
N.A.
99
N.A.
N.A.
88.1
98.1
96.3
93.6
N.A.
76.1
83.7
79
85.8
P-Site Identity:
100
100
6.6
0
N.A.
100
N.A.
N.A.
93.3
93.3
80
73.3
N.A.
46.6
60
46.6
66.6
P-Site Similarity:
100
100
13.3
13.3
N.A.
100
N.A.
N.A.
100
100
93.3
93.3
N.A.
66.6
73.3
80
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
31
27.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.9
55.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
40
0
0
0
7
14
7
0
0
7
67
40
7
74
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
14
67
27
80
7
0
0
0
80
20
0
0
0
0
% D
% Glu:
0
0
20
40
14
0
0
7
7
14
67
0
7
0
0
% E
% Phe:
0
0
0
7
0
0
0
7
0
0
0
7
0
0
0
% F
% Gly:
0
7
0
0
0
7
0
0
0
0
0
0
0
0
0
% G
% His:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
7
7
0
0
0
0
0
0
0
0
0
0
7
14
0
% I
% Lys:
0
0
0
0
0
7
0
0
0
0
0
0
0
14
0
% K
% Leu:
60
27
0
20
0
0
7
0
80
7
0
0
14
14
0
% L
% Met:
0
7
0
0
0
0
7
7
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
14
7
0
0
0
0
7
0
7
0
% N
% Pro:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
7
% P
% Gln:
7
0
14
0
7
0
0
0
7
0
0
14
0
0
14
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
7
% R
% Ser:
0
0
0
7
0
20
67
0
0
0
0
0
7
47
0
% S
% Thr:
0
0
0
0
0
40
0
0
0
0
7
0
7
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
7
14
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
74
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _