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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MPP6
All Species:
35.15
Human Site:
Y387
Identified Species:
55.24
UniProt:
Q9NZW5
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NZW5
NP_057531.2
540
61117
Y387
D
E
K
D
G
Q
A
Y
K
F
V
S
R
S
E
Chimpanzee
Pan troglodytes
XP_001159242
552
62429
Y399
D
E
K
D
G
Q
A
Y
K
F
V
S
R
S
E
Rhesus Macaque
Macaca mulatta
XP_001096776
582
65885
Y429
D
E
K
D
G
Q
A
Y
K
F
V
S
R
S
E
Dog
Lupus familis
XP_539479
540
61070
Y387
D
E
K
D
G
Q
A
Y
K
F
V
S
R
S
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLB0
553
62612
Y400
D
E
K
D
G
Q
A
Y
K
F
V
S
R
S
E
Rat
Rattus norvegicus
Q62915
909
103240
H756
R
F
A
Y
P
I
P
H
T
T
R
P
P
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507958
540
61012
Y387
D
E
K
D
G
Q
A
Y
K
F
V
S
R
A
E
Chicken
Gallus gallus
Q5ZJ00
468
52501
P315
N
P
E
K
F
M
Y
P
P
P
Y
T
T
R
P
Frog
Xenopus laevis
NP_001084783
538
60687
Y385
D
E
K
D
G
H
A
Y
R
F
V
S
R
V
E
Zebra Danio
Brachydanio rerio
Q6P0D7
576
65174
Y417
Q
E
S
E
G
V
E
Y
H
F
I
S
K
N
L
Tiger Blowfish
Takifugu rubipres
P49697
467
52590
H317
K
F
S
Y
P
V
P
H
T
T
R
P
Q
R
K
Fruit Fly
Dros. melanogaster
Q24210
898
100893
R748
Y
P
I
P
H
T
T
R
P
A
K
P
E
E
E
Honey Bee
Apis mellifera
XP_391909
602
67965
Y448
L
E
E
D
G
K
S
Y
W
F
I
D
R
E
S
Nematode Worm
Caenorhab. elegans
P54936
961
108794
H808
R
F
A
Y
P
I
P
H
T
T
R
P
P
R
K
Sea Urchin
Strong. purpuratus
XP_791632
556
63023
Y403
G
E
K
S
G
V
E
Y
H
F
V
L
R
S
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.8
92.7
99.6
N.A.
95.8
30
N.A.
96.8
37.7
86.8
37.8
35.3
28.8
42.3
28.6
48.7
Protein Similarity:
100
97.8
92.7
100
N.A.
96.9
42.5
N.A.
99.2
55.3
94.8
55.9
55.5
41.8
63.7
39.9
67.9
P-Site Identity:
100
100
100
100
N.A.
100
0
N.A.
93.3
0
80
33.3
0
6.6
40
0
53.3
P-Site Similarity:
100
100
100
100
N.A.
100
13.3
N.A.
100
20
86.6
60
20
6.6
66.6
13.3
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
14
0
0
0
47
0
0
7
0
0
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
47
0
0
54
0
0
0
0
0
0
0
7
0
0
7
% D
% Glu:
0
67
14
7
0
0
14
0
0
0
0
0
7
14
54
% E
% Phe:
0
20
0
0
7
0
0
0
0
67
0
0
0
0
0
% F
% Gly:
7
0
0
0
67
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
7
7
0
20
14
0
0
0
0
0
0
% H
% Ile:
0
0
7
0
0
14
0
0
0
0
14
0
0
0
0
% I
% Lys:
7
0
54
7
0
7
0
0
40
0
7
0
7
7
20
% K
% Leu:
7
0
0
0
0
0
0
0
0
0
0
7
0
0
7
% L
% Met:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% N
% Pro:
0
14
0
7
20
0
20
7
14
7
0
27
14
0
7
% P
% Gln:
7
0
0
0
0
40
0
0
0
0
0
0
7
0
0
% Q
% Arg:
14
0
0
0
0
0
0
7
7
0
20
0
60
20
0
% R
% Ser:
0
0
14
7
0
0
7
0
0
0
0
54
0
40
7
% S
% Thr:
0
0
0
0
0
7
7
0
20
20
0
7
7
0
0
% T
% Val:
0
0
0
0
0
20
0
0
0
0
54
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% W
% Tyr:
7
0
0
20
0
0
7
67
0
0
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _