KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MPP6
All Species:
36.06
Human Site:
Y327
Identified Species:
56.67
UniProt:
Q9NZW5
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NZW5
NP_057531.2
540
61117
Y327
D
R
H
E
I
Q
I
Y
E
E
V
A
K
M
P
Chimpanzee
Pan troglodytes
XP_001159242
552
62429
Y339
D
R
H
E
I
Q
I
Y
E
E
V
A
K
M
P
Rhesus Macaque
Macaca mulatta
XP_001096776
582
65885
Y369
D
R
H
E
I
Q
I
Y
E
E
V
A
K
M
P
Dog
Lupus familis
XP_539479
540
61070
Y327
D
R
H
E
I
Q
I
Y
E
E
V
A
K
M
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLB0
553
62612
Y340
D
R
H
E
I
Q
I
Y
E
E
V
A
K
M
P
Rat
Rattus norvegicus
Q62915
909
103240
Y696
F
G
K
K
K
K
Q
Y
K
D
K
Y
L
A
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507958
540
61012
Y327
D
R
H
E
I
Q
I
Y
E
E
V
A
K
M
P
Chicken
Gallus gallus
Q5ZJ00
468
52501
D255
G
K
K
K
K
Y
K
D
K
Y
L
A
K
H
S
Frog
Xenopus laevis
NP_001084783
538
60687
Y325
D
R
H
E
I
Q
I
Y
E
E
V
A
R
M
P
Zebra Danio
Brachydanio rerio
Q6P0D7
576
65174
V357
D
V
P
T
Y
E
E
V
T
T
Y
R
R
K
H
Tiger Blowfish
Takifugu rubipres
P49697
467
52590
L257
K
K
C
K
D
K
Y
L
A
K
H
S
S
I
F
Fruit Fly
Dros. melanogaster
Q24210
898
100893
F688
L
A
K
H
N
A
I
F
D
T
L
D
V
V
T
Honey Bee
Apis mellifera
XP_391909
602
67965
Y388
D
S
A
E
L
L
L
Y
E
E
V
A
R
M
P
Nematode Worm
Caenorhab. elegans
P54936
961
108794
L748
K
Y
Y
T
T
K
Y
L
Q
K
H
S
A
L
F
Sea Urchin
Strong. purpuratus
XP_791632
556
63023
Y343
D
R
S
D
I
V
I
Y
E
E
V
Q
E
M
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.8
92.7
99.6
N.A.
95.8
30
N.A.
96.8
37.7
86.8
37.8
35.3
28.8
42.3
28.6
48.7
Protein Similarity:
100
97.8
92.7
100
N.A.
96.9
42.5
N.A.
99.2
55.3
94.8
55.9
55.5
41.8
63.7
39.9
67.9
P-Site Identity:
100
100
100
100
N.A.
100
6.6
N.A.
100
13.3
93.3
6.6
0
6.6
60
0
66.6
P-Site Similarity:
100
100
100
100
N.A.
100
33.3
N.A.
100
40
100
20
40
33.3
80
40
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
7
0
0
7
0
0
7
0
0
60
7
7
0
% A
% Cys:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
67
0
0
7
7
0
0
7
7
7
0
7
0
0
0
% D
% Glu:
0
0
0
54
0
7
7
0
60
60
0
0
7
0
0
% E
% Phe:
7
0
0
0
0
0
0
7
0
0
0
0
0
0
14
% F
% Gly:
7
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
47
7
0
0
0
0
0
0
14
0
0
7
7
% H
% Ile:
0
0
0
0
54
0
60
0
0
0
0
0
0
7
0
% I
% Lys:
14
14
20
20
14
20
7
0
14
14
7
0
47
7
7
% K
% Leu:
7
0
0
0
7
7
7
14
0
0
14
0
7
7
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
60
0
% M
% Asn:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
60
% P
% Gln:
0
0
0
0
0
47
7
0
7
0
0
7
0
0
0
% Q
% Arg:
0
54
0
0
0
0
0
0
0
0
0
7
20
0
0
% R
% Ser:
0
7
7
0
0
0
0
0
0
0
0
14
7
0
7
% S
% Thr:
0
0
0
14
7
0
0
0
7
14
0
0
0
0
7
% T
% Val:
0
7
0
0
0
7
0
7
0
0
60
0
7
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
7
0
7
7
14
67
0
7
7
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _