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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MPP6
All Species:
35.76
Human Site:
S493
Identified Species:
56.19
UniProt:
Q9NZW5
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NZW5
NP_057531.2
540
61117
S493
L
K
K
T
V
D
E
S
A
R
I
Q
R
A
Y
Chimpanzee
Pan troglodytes
XP_001159242
552
62429
S505
L
K
K
T
V
D
E
S
A
R
I
Q
R
A
Y
Rhesus Macaque
Macaca mulatta
XP_001096776
582
65885
S535
L
K
K
T
V
D
E
S
A
R
I
Q
R
A
Y
Dog
Lupus familis
XP_539479
540
61070
S493
L
K
K
T
V
D
E
S
A
R
I
Q
R
A
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLB0
553
62612
S506
L
K
K
T
V
D
E
S
A
R
I
Q
R
A
Y
Rat
Rattus norvegicus
Q62915
909
103240
S862
L
Q
R
L
Q
K
E
S
D
V
L
Q
R
T
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507958
540
61012
S493
L
K
K
T
V
D
E
S
A
R
I
Q
R
A
Y
Chicken
Gallus gallus
Q5ZJ00
468
52501
S421
L
Q
Q
L
R
K
D
S
E
S
I
R
S
R
Y
Frog
Xenopus laevis
NP_001084783
538
60687
S491
L
K
K
T
V
D
E
S
A
R
V
M
R
A
Y
Zebra Danio
Brachydanio rerio
Q6P0D7
576
65174
E523
F
S
E
E
D
F
L
E
M
I
S
A
S
Q
M
Tiger Blowfish
Takifugu rubipres
P49697
467
52590
I423
I
Q
K
E
S
E
T
I
L
N
T
Y
R
Q
Y
Fruit Fly
Dros. melanogaster
Q24210
898
100893
L854
L
A
K
E
S
E
M
L
R
Q
L
Y
G
H
F
Honey Bee
Apis mellifera
XP_391909
602
67965
E554
D
L
K
A
T
L
E
E
S
A
A
L
Q
R
A
Nematode Worm
Caenorhab. elegans
P54936
961
108794
S914
L
E
K
L
L
N
E
S
D
V
L
R
Q
A
F
Sea Urchin
Strong. purpuratus
XP_791632
556
63023
I509
T
V
E
E
S
A
R
I
E
R
Q
Y
S
H
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.8
92.7
99.6
N.A.
95.8
30
N.A.
96.8
37.7
86.8
37.8
35.3
28.8
42.3
28.6
48.7
Protein Similarity:
100
97.8
92.7
100
N.A.
96.9
42.5
N.A.
99.2
55.3
94.8
55.9
55.5
41.8
63.7
39.9
67.9
P-Site Identity:
100
100
100
100
N.A.
100
40
N.A.
100
26.6
86.6
0
20
13.3
13.3
33.3
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
60
N.A.
100
53.3
93.3
6.6
40
40
26.6
80
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
7
0
7
0
0
47
7
7
7
0
54
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
0
7
47
7
0
14
0
0
0
0
0
0
% D
% Glu:
0
7
14
27
0
14
67
14
14
0
0
0
0
0
0
% E
% Phe:
7
0
0
0
0
7
0
0
0
0
0
0
0
0
14
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
14
0
% H
% Ile:
7
0
0
0
0
0
0
14
0
7
47
0
0
0
0
% I
% Lys:
0
47
74
0
0
14
0
0
0
0
0
0
0
0
0
% K
% Leu:
74
7
0
20
7
7
7
7
7
0
20
7
0
0
7
% L
% Met:
0
0
0
0
0
0
7
0
7
0
0
7
0
0
7
% M
% Asn:
0
0
0
0
0
7
0
0
0
7
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
20
7
0
7
0
0
0
0
7
7
47
14
14
0
% Q
% Arg:
0
0
7
0
7
0
7
0
7
54
0
14
60
14
0
% R
% Ser:
0
7
0
0
20
0
0
67
7
7
7
0
20
0
0
% S
% Thr:
7
0
0
47
7
0
7
0
0
0
7
0
0
7
0
% T
% Val:
0
7
0
0
47
0
0
0
0
14
7
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
20
0
0
67
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _